Results 91 to 100 of about 476,420 (328)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Flexible query processing of SPARQL queries [PDF]
, 2018 SPARQL is the predominant language for querying RDF data, which is the standard model for representing web data and more specifically Linked Open Data (a collection of heterogeneous connected data). Datasets in RDF form can be hard to query by a user if she does not have a full knowledge of the structure of the dataset.
openaire +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
GeoSpark SQL: An Effective Framework Enabling Spatial Queries on Spark
ISPRS International Journal of Geo-Information, 2017 In the era of big data, Internet-based geospatial information services such as various LBS apps are deployed everywhere, followed by an increasing number of queries against the massive spatial data.
Zhou Huang +3 more
doaj +1 more source
Edgelet Computing: Pushing Query Processing and Liability at the Extreme Edge of the Network
, 2022 Ludovic Javet +3 more
openalex +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Retracted: Location-Dependent Query Processing: Semantic Cache for Real-Time Smart City Analytics. [PDF]
Appl Bionics Biomech, 2023 And Biomechanics AB.
europepmc +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Optimizing Skyline Query Processing in Incomplete Data
IEEE Access, 2019 Given the significance of skyline queries, they are incorporated in various modern applications including personalized recommendation systems as well as decision-making and decision-support systems.
Yonis Gulzar +2 more
doaj +1 more source