Results 61 to 70 of about 102,125 (260)

Survey on AI Powered New Techniques for Query Processing and Optimization

open access: yesJisuanji kexue yu tansuo, 2020
As one of the most challenging problems in data management, query processing and optimization are always widely concerned by researchers. However, it is very difficult for traditional techniques to meet the diverse requirements of modern database system ...
SONG Yumeng, GU Yu, LI Fangfang, YU Ge
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

DISPAQ: Distributed Profitable-Area Query from Big Taxi Trip Data

open access: yesSensors, 2017
One of the crucial problems for taxi drivers is to efficiently locate passengers in order to increase profits. The rapid advancement and ubiquitous penetration of Internet of Things (IoT) technology into transportation industries enables us to provide ...
Fadhilah Kurnia Putri   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Advanced processing for ontological queries

open access: yesProceedings of the VLDB Endowment, 2010
Ontology-based data access is a powerful form of extending database technology, where a classical extensional database (EDB) is enhanced by an ontology that generates new intensional knowledge which may contribute to answer a query.
CALÌ A, Georg Gottlob, Andreas Pieris
openaire   +3 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Probabilistic CkNN Queries of Uncertain Data in Large Road Networks

open access: yesIEEE Access, 2016
Continuous k-nearest neighbor (CkNN) query processing is an important issue in spatial temporal databases. In real-world scenarios, query clients and data objects may move with uncertain speeds on the road networks, which makes retrieving the exact CkNN ...
Yanhong Li   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Smart Intra-query Fault Tolerance for Massive Parallel Processing Databases

open access: yesData Science and Engineering, 2019
Intra-query fault tolerance has increasingly been a concern for online analytical processing, as more and more enterprises migrate data analytical systems from mainframes to commodity computers.
Yunhong Ji   +4 more
doaj   +1 more source

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