Results 91 to 100 of about 1,560,042 (297)
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Question Answering System for Applicant Support by Using Modern Messengers
Моделирование и анализ информационных систем, 2018 There is an increasing interest to the instant messaging applications, messengers. These applications allow us to interact with other users and include a functionality that can help us to implement bots that automate various business processes or provide
Dmitry R. Filonov +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Analysis and optimization of question answering systems
, 2023 DOCTORAT EN ARQUITECTURA I TECNOLOGIA DE COMPUTADORS (Pla 1998)
openaire +4 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
AN AUTOMATIC WEB-BASED QUESTION ANSWERING SYSTEM FOR E-LEARNING
Інформаційні технології і засоби навчання, 2017 An automatic web based Question Answering (QA) system is a valuable tool for improving e-learning and education. Several approaches employ natural language processing technology to understand questions given in natural language text, which is incomplete ...
Waheeb Ahmed, Babu Anto
doaj
DiaRAG: intelligent question-answering system for the diabetes domain
工程科学学报To address the dual requirements of efficiency and professionalism in diabetes-related intelligent question-answering, this study presents DiaRAG, an innovative system that synergistically integrates knowledge graphs with retrieval-augmented generation ...
Tao YANG +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Self-Wiring Question Answering Systems
CoRR, 2016 Question answering (QA) has been the subject of a resurgence over the past years. The said resurgence has led to a multitude of question answering (QA) systems being developed both by companies and research facilities. While a few components of QA systems get reused across implementations, most systems do not leverage the full potential of component ...
Ricardo Usbeck +3 more
openaire +2 more sources