Results 51 to 60 of about 4,505,795 (313)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

In dogs with chronic enteropathy (idiopathic inflammatory bowel disease) is budesonide more effective than prednisolone or prednisone in resolving clinical signs?

open access: yesVeterinary Evidence, 2023
PICO Question In dogs with chronic enteropathy (idiopathic inflammatory bowel disease) is budesonide more effective than prednisolone or prednisone in resolving clinical signs or improving the canine inflammatory bowel disease (IBD) activity index ...
Victoria Alice Coates
doaj   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

Does Physical Therapy after a TPLO Lead to Improvement of the 1-Year Post-Operative Peak Vertical Force?

open access: yesVeterinary Evidence, 2016
Clinical bottom lineBased  on the lack of sufficient clinical studies investigating the PICO question, it is not possible to conclude if physical therapy should be recommended as a routine postoperative treatment after TPLO. 
Andrea Faure Beaulieu, Antonio Pozzi
doaj   +1 more source

Managing atopic dermatitis in dogs: are antihistamines as effective as glucocorticoids?

open access: yesVeterinary Evidence, 2020
PICO question In dogs with atopic dermatitis, are antihistamines as effective as glucocorticoids at reducing the severity of clinical signs?   Clinical bottom line Category of research question Treatment The number and type of study ...
Sarah Long
doaj   +1 more source

Can straw based enrichment treat tail biting in pigs?

open access: yesVeterinary Evidence, 2022
PICO question Can straw based enrichment be used successfully as a treatment intervention to reduce tail biting injuries in weaner to finisher pigs housed in indoor farming systems?
Abigail Liston
doaj   +1 more source

Energy Efficiency of Downlink Networks with Caching at Base Stations

open access: yes, 2016
Caching popular contents at base stations (BSs) can reduce the backhaul cost and improve the network throughput. Yet whether locally caching at the BSs can improve the energy efficiency (EE), a major goal for 5th generation cellular networks, remains ...
Liu, Dong, Yang, Chenyang
core   +1 more source

Non-Clinical Benefits of Evidence - Based Veterinary Medicine [PDF]

open access: yes, 2016
Clinical bottom lineThere are few studies addressing business benefits of EBVM.While the need for a wider adoption of EBVM has been highlighted and linked to commercial benefits, further empirical studies are needed to identify and quantify such linkages.
Hauser, S, Jackson, E L
core   +5 more sources

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

How to use the International Classification of Functioning, Disability and Health as a reference system for comparative evaluation and standardized reporting of rehabilitation interventions [PDF]

open access: yes, 2019
Rehabilitation aims to optimize functioning of persons experiencing functioning limitations. As such the comparative evaluation of rehabilitation interventions relies on the analysis of the differences between the change in patient functioning after a ...
Cleeland CS   +4 more
core   +1 more source

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