Results 61 to 70 of about 32,814 (251)
Do Palliative Steroids Prolong Survival in Dogs With Multicentric Lymphoma?
Veterinary Evidence, 2018 PICO questionIn dogs with naturally occurring multicentric B cell lymphoma does treatment with glucocorticoids alone extend survival time when compared to no treatment?Clinical bottom line There is weak evidence, due to insufficient studies with ...
Clare M Knottenbelt
doaj +1 more source
Defining and Measuring Developmental Regression During Childhood: A Scoping Review
Autism Research, EarlyView.ABSTRACT Developmental regression during childhood is inconsistently defined and measured, resulting in delayed diagnostic discovery and intervention. This study aimed to examine published definitions and measures for developmental regression. A comprehensive search strategy was applied to Medline, Embase, Cochrane, and PsycINFO databases.
Kirsten Furley +4 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim The aim of this systematic review was to assess all available clinical data regarding the use of a single dose of basiliximab in solid organ transplantation compared to the standard double dosage, with particular interest in efficacy, safety and cost‐savings.
Alessio Provenzani +4 more
wiley +1 more source
The peri / postoperative analgesic effect of intravenous paracetamol in dogs
Veterinary EvidencePICO Question In healthy dogs undergoing a surgical procedure, is there improved pain control in dogs receiving intravenous paracetamol in the peri / postoperative period compared to dogs not receiving intravenous paracetamol?
Laura Mckay
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk +5 more
wiley +1 more source
Formulating the Evidence Based Practice Question: A Review of the Frameworks
Evidence Based Library and Information Practice, 2011 IntroductionQuestions are the driving force behind evidence based practice (EBP) (Eldredge, 2000). If there were no questions, EBP would be unnecessary. Evidence based practice questions focus on practical real-world problems and issues.
Karen Sue Davies
doaj
Known-Item Retrieval Performance of a PICO-based Medical Question Answering Engine
Asia Pacific Journal of Information Systems, 2015 The performance of a novel medical question-answering engine called CliniCluster and existing search engines, such as CQA-1.0, Google, and Google Scholar, was evaluated using known-item searching. Known-item searching is a document that has been critically appraised to be highly relevant to a therapy question.
Vong, Wan-Tze, Then, Patrick Hang Hui
openaire +2 more sources
How the HTAR will contribute to a value‐based decision‐making for medicinal products across the EU
British Journal of Clinical Pharmacology, EarlyView.The European Union Health Technology Regulation 2021/2282 (HTAR) introduces joint assessment of health technologies (including medicinal products and medical devices) across EU Member States. It was signed into law in 2021 and came into full force in January 2025.
Roisin Adams, Michal Stanak
wiley +1 more source
Regulatory harmonization: Evolution, globalization and future directions
British Journal of Clinical Pharmacology, EarlyView.Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm +2 more
wiley +1 more source
“We need to talk about PICO”: Approaching the move from question formulation to search strategy
Journal of Health Information and Libraries Australasia, 2023 This paper begins with PICO and its place in health librarianship, before moving to discuss a model of teaching knowledge that may offer some new ways of thinking about PICO (or, perhaps, leaving PICO behind). My two main points of contention with the ubiquity of PICO in health librarianship are: That it is only one among many approaches to ...
openaire +1 more source