Results 81 to 90 of about 4,203,771 (322)

Análise de proveniência das contas verdes dos Perdigões [PDF]

, 2010
A variscite é um mineral raro que oferece uma excelente opotunidade de estudo dos padrões de comércio e troca na Europa durante a Pré- História através da determinação da sua fonte de proveniência.
Hurtado Pérez, Víctor, Linares Catela, José Antonio, Odriozola Lloret, Carlos Patricio   +2 more
core  

Is natural higgsino-only dark matter excluded?

, 2018
The requirement of electroweak naturalness in supersymmetric (SUSY) models of particle physics necessitates light higgsinos not too far from the weak scale characterized by m(weak)~ m(W,Z,h)~100 GeV.
Baer, Howard, Barger, Vernon, Sengupta, Dibyashree, Tata, Xerxes   +3 more
core   +1 more source

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

Do Palliative Steroids Prolong Survival in Dogs With Multicentric Lymphoma?

Veterinary Evidence, 2018
PICO questionIn dogs with naturally occurring multicentric B cell lymphoma does treatment with glucocorticoids alone extend survival time when compared to no treatment?Clinical bottom line There is weak evidence, due to insufficient studies with ...
Clare M Knottenbelt
doaj   +1 more source

RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication

Advanced Science, EarlyView.
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song, Zuomeng Wu, Yixiang Dong, Yunxiong Fang, Shiyu Bian, Daokuan Wang, Huang Fang, Yunlei Liu, Wang Ying, Jun Qian, Tianyu Han, Cailiang Shen   +11 more
wiley   +1 more source

Text Network Analysis to Develop a Search Strategy for a Systematic Review

Applied Sciences
Setting the population, intervention, comparison, and outcome (PICO) elements during a search strategy development stage for a systematic review (SR) defines a research question specifically.
Subeen Leem, Jieun Shin, Jong-Yeup Kim, Sung Ryul Shim   +3 more
doaj   +1 more source

Lost in Translation: Piloting a Novel Framework to Assess the Challenges in Translating Scientific Uncertainty From Empirical Findings to WHO Policy Statements. [PDF]

, 2017
BACKGROUND:Calls for evidence-informed public health policy, with implicit promises of greater program effectiveness, have intensified recently. The methods to produce such policies are not self-evident, requiring a conciliation of values and norms ...
Benmarhnia, Tarik, Huang, Jonathan Y, Jones, Catherine M   +2 more
core   +2 more sources

Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure

European Respiratory Journal, 2017
Noninvasive mechanical ventilation (NIV) is widely used in the acute care setting for acute respiratory failure (ARF) across a variety of aetiologies. This document provides European Respiratory Society/American Thoracic Society recommendations for the ...
B. Rochwerg, L. Brochard, M. Elliott, D. Hess, N. Hill, S. Nava, P. Navalesi, M. Antonelli, J. Brożek, G. Conti, M. Ferrer, K. Guntupalli, S. Jaber, S. Keenan, J. Mancebo, S. Mehta, S. Raoof   +16 more
semanticscholar   +1 more source

Data‐Driven Feedback Identifies Focused Ultrasound Exposure Regimens for Improved Nanotheranostic Targeting of the Brain

Advanced Science, EarlyView.
Machine learning models predict in real time the onset of harmful microbubble collapse during microbubble‐enhanced focused ultrasound (MB‐FUS) and enable dynamic adjustment of sonication to prevent cavitation‐induced damage. This predictive control expands the safe operating window for bloodbrain barrier opening, enhancing nanoparticle delivery and ...
Hohyun Lee, Victor Menezes, Shiqin Zeng, Chulyong Kim, Cynthia M. Baseman, Jae Hyun Kim, Samhita Padmanabhan, Pranav Premdas, Naima Djeddar, Anton Bryksin, Nikhil Pandey, Pavlos Anastasiadis, Anthony J. Kim, Tobey J. MacDonald, Chetan Bettegowda, Graeme F. Woodworth, Felix J. Herrmann, Costas Arvanitis   +17 more
wiley   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source