Results 91 to 100 of about 4,525,545 (359)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

The Use of Hedges in Tertiary EFL Students' Presentation

English Review: Journal of English Education, 2015
The main objective of language education is to enable students to communicate effectively. In order to achieve that objective, students need to master pragmatic competence.
Ihsan Nur Iman Faris
doaj  

Current scholarship and future questions on delayed school start times for adolescents’ sleep and well-being [PDF]

, 2018
Amy R. Wolfson
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A case of fatal pulmonary embolism raising questions about the dosing regimen for dalteparin in the very obese [PDF]

, 2008
Andrew Walden, R.A. Levison, Sudir Singh, David Keeling   +3 more
openalex   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

To Use Constructed-Response Questions, Or Not To Use Constructed-Response Questions? That Is The Question [PDF]

Advocates of Constructed Response (CR) questions argue that CR questions provide a different assessment of student knowledge than is available from Multiple Choice (MC) questions. If that is the case, and if the benefit in terms of improved assessment is
Stephen Hickson, W. Robert Reed, Nicholas Sander   +2 more
core  

Proceedings of the Workshop on Machine Reading for Question Answering [PDF]

, 2018
Yichen Gong, Samuel Bowman, Martı́n Abadi, Ashish Agarwal, Paul Barham, Eugene Brevdo, Zhifeng Chen, Craig Citro, Greg Cor- Rado, Andy Davis, Jeffrey Dean, Matthieu Devin, Sanjay Ghemawat, Ian Goodfellow, Andrew Harp, Geoffrey Irving, Michael Isard, Yangqing Jia, Rafał Józefowicz, Łukasz Kaiser, Manjunath Kudlur, Josh Levenberg, Dan Mané, Rajat Monga, Sherry Moore, Derek G. Murray, Chris Olah, Mike Schuster, Jonathon Shlens, Benoit Steiner, Ilya Sutskever, Kunal Tal- War, Paul A. Tucker, Vincent Vanhoucke, Vijay Vasude- Van, Fernanda Viégas, Oriol Vinyals, Pete Warden, Mir Rosenberg, Song Xia, Jianfeng Gao, Saurabh Tiwary, Marc-Antoine Rondeau, Timothy J. Hazen, Seunghak Yu, Sathish Reddy Indurthi, Seohyun Back, Haejun Lee, Jörg Franke, Jan Niehues, Alex Waibel, Michael Boratko, Harshit Padigela, Divyendra Mikkilineni, Pritish Yuvraj, Rajarshi Das, Andrew McCallum, Maria Chang, Achille Fokoue-Nkoutche, Pavan Kapanipathi, Nicholas Mattei, Ryan Musa, Kartik Talamadupula, Michael Witbrock, Boratko Michael, Fokoue-Nkoutche Achille, Franke Jörg, Wei He, Sathish Reddy, Xuan Liu, Wadhwa Soumya, Samuel, Chandu, Khyathi, Chang, Das, Rajarshi, Du, Ye, Fokoue-Nkoutche Achille, Franke Jrg, Gong, Yichen, Wei He, Sathish Reddy, Kapanipathi, Pavan, Lee, Liu, Kai, Xuan Liu, Yuan, Lyu, Yajuan, Mattei, Nicholas, Mikkilineni, Divyendra, Nyberg, Padigela   +99 more
openalex   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

La laïcité à l’école et ses représentations chez les lycéens

, 2017
Par Fabienne Bontempi, professeure agrégée de lettres modernes, référente laïcité de l'Académie de Toulouse (2015-2017) ; DU "Politique, Religion, Laïcité" Télécharger l'article Contexte et objectifs de l’étude Quel héritage pour la transmission des ...
(Nouvelles) Questions Sociales
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