Results 81 to 90 of about 10,401,890 (300)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Thanks to the CHIVA strategy, may the histoarchitecture of great saphenous vein-sparing, make it suitable as graft for bypasses?

Veins and Lymphatics, 2019
Not ...
Roberto Delfrate
doaj   +1 more source

Perspectives, Questions, and Epistemic Value [PDF]

, 2019
Many epistemologists endorse true-belief monism, the thesis that only true beliefs are of fundamental epistemic value. However, this view faces formidable counterexamples.
Khalifa, Kareem, Millson, Jared A.
core  

Learning by Asking Questions

, 2017
We introduce an interactive learning framework for the development and testing of intelligent visual systems, called learning-by-asking (LBA). We explore LBA in context of the Visual Question Answering (VQA) task.
Fergus, Rob, Girshick, Ross, Gupta, Abhinav, Hebert, Martial, Misra, Ishan, van der Maaten, Laurens   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

INSTITUTIONS ET POLITIQUES DANS LES PAYS EMERGENTS : UNE LECTURE INSTITUTIONNALISTE COMPAREE

Regard lucide
Cet article explore les interactions entre institutions et politiques économiques dans le contexte des pays dits émergents. À travers une comparaison approfondie du Brésil, du Vietnam, de l’Afrique du Sud et du Maroc, il montre que les trajectoires d ...
Augustin KUPA MUKADI
doaj  

LTAG semantics for questions [PDF]

, 2004
This papers presents a compositional semantic analysis of interrogatives clauses in LTAG (Lexicalized Tree Adjoining Grammar) that captures the scopal properties of wh- and nonwh-quantificational elements.
Babko-Malaya, Olga, Kallmeyer, Laura, Romero, Maribel   +2 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Physical Intelligence and Thermodynamic Computing

Entropy, 2017
This paper proposes that intelligent processes can be completely explained by thermodynamic principles. They can equally be described by information-theoretic principles that, from the standpoint of the required optimizations, are functionally equivalent.
Robert L. Fry
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source