Results 1 to 10 of about 38,240 (235)

Post‐marketing surveillance of quetiapine fumarate extended‐release tablets in patients with bipolar depression [PDF]

Neuropsychopharmacology Reports
Aim This study aimed to verify the real‐world efficacy and safety of quetiapine fumarate extended‐release tablets (Bipresso® 50 mg and 150 mg; marketing authorization holder is KYOWA Pharmaceutical Industry Co., Ltd., Osaka, Japan) in patients with ...
Taro Kishi, Nakao Iwata, Hiroyuki Irie, Masaru Aikawa   +3 more
doaj   +4 more sources

Hemodialysis Treatment for High-Dose Quetiapine Fumarate Poisoning: A Case Report [PDF]

Case Reports in Nephrology and Dialysis
Introduction: Quetiapine is a new atypical antipsychotic with minor side effects. There have been few reports of rhabdomyolysis and acute kidney injury associated with quetiapine overdose.
Jiaoyang Li, Zhiqin Chen, Shuran Qian, Xuemei Liu   +3 more
doaj   +5 more sources

Interaction of Heavy Drinking Patterns and Depression Severity Predicts Efficacy of Quetiapine Fumarate XR in Lowering Alcohol Intake in Alcohol Use Disorder Patients [PDF]

Substance Abuse: Research and Treatment, 2020
Background: Shared etiological pathways of dopamine and serotonin neurotransmission play a central role in heavy alcohol intake and exacerbation in the symptoms of depression. We investigated the treatment efficacy of Quetiapine fumarate extended release
Vatsalya Vatsalya, Maiying Kong, Luis M Marsano, Zimple Kurlawala, Kan V Chandras, Melanie L Schwandt, Vijay A Ramchandani, Craig J McClain   +7 more
doaj   +6 more sources

Effect of Polymers and Permeation Enhancers in the Release of Quetiapine Fumarate Transdermal Patch through the Dialysis Membrane. [PDF]

Polymers (Basel), 2022
Quetiapine Fumarate is potent, and the daily therapeutic dose can be delivered easily across the skin with the help of permeation enhancers. Quetiapine Fumarate-loaded transdermal patches were prepared by solvent evaporation technique.
Bhupathyraaj M, Vijaya Rani KR, Sridhar SB, Shareef J, Thomas S, Halligudi N, Sockalingam A, Mohandoss K, Sundar S.   +8 more
europepmc   +4 more sources

Central Composite Optimization of Glycerosomes for the Enhanced Oral Bioavailability and Brain Delivery of Quetiapine Fumarate [PDF]

Pharmaceuticals, 2022
This study aimed to formulate and statistically optimize glycerosomal formulations of Quetiapine fumarate (QTF) to increase its oral bioavailability and enhance its brain delivery.
Randa Mohammed Zaki, Munerah M. Alfadhel, Manal A. Alossaimi, Lara Ayman Elsawaf, Vidya Devanathadesikan Seshadri, Alanood S. Almurshedi, Rehab Mohammad Yusif, Mayada Said   +7 more
doaj   +3 more sources

Self-emulsifying Drug Delivery System for Improved Dissolution and Oral Absorption of Quetiapine Fumarate: Investigation of Drug Release Mechanism and In-vitro Intestinal Permeability. [PDF]

Iran J Pharm Res, 2021
In this study, we focused on quetiapine fumarate (QTF), a class II BCS drug. QTF is an atypical antipsychotic used in the treatment of schizophrenia and bipolar disorders.
Ayed OBH, Lassoued MA, Bahloul B, Sfar S.   +3 more
europepmc   +4 more sources

Brain Targeting of Quetiapine Fumarate via Intranasal Delivery of Loaded Lipospheres: Fabrication, In-Vitro Evaluation, Optimization, and In-Vivo Assessment [PDF]

Pharmaceuticals, 2022
A liposphere system for intranasal delivery of quetiapine fumarate (QTF) was created to assess the potential for enhanced drug delivery. We investigated the effects of particle size, entrapment effectiveness, poly dispersibility index, and pluronic ...
Randa Mohammed Zaki, Mohammed F. Aldawsari, Manal A. Alossaimi, Shaikah F. Alzaid, Vidya Devanathadesikan Seshadri, Alanood S. Almurshedi, Basmah Nasser Aldosari, Rehab Mohammad Yusif, Ossama M. Sayed   +8 more
doaj   +3 more sources

The Influence of Prenatal Exposure to Quetiapine Fumarate on the Development of Dopaminergic Neurons in the Ventral Midbrain of Mouse Embryos. [PDF]

Int J Mol Sci, 2022
The effects of second-generation antipsychotics on prenatal neurodevelopment, apoptotic neurodegeneration, and postnatal developmental delays have been poorly investigated.
Alsanie WF, Abdelrahman S, Alhomrani M, Gaber A, Alosimi EA, Habeeballah H, Alkhatabi HA, Felimban RI, Hauser CAE, Tayeb HH, Alamri AS, Alamri A, Raafat BM, Alswat KA, Althobaiti YS, Asiri YA.   +15 more
europepmc   +4 more sources

Influence of physico-chemical properties of hydroxypropyl methylcellulose on quetiapine fumarate release from sustained release matrix tablets [PDF]

BMC Chemistry
Quetiapine fumarateis a typical antipsychotic with a short half-life of 6 h and is administered multiple times daily. In this study, a copolymer for controlled delivery of quetiapine fumarate will be developed.
Takwa E. Ellakwa, Ahmad S. Abu-Khadra, Doha El-Sayed Ellakwa   +2 more
doaj   +3 more sources

Formulation Development of Solid Self-Nanoemulsifying Drug Delivery Systems of Quetiapine Fumarate via Hot-Melt Extrusion Technology: Optimization Using Central Composite Design [PDF]

Pharmaceutics
Quetiapine fumarate (QTF) was approved for the treatment of schizophrenia and acute manic episodes. QTF can also be used as an adjunctive treatment for major depressive disorders. QTF oral bioavailability is limited due to its poor aqueous solubility and
Prateek Uttreja, Ahmed Adel Ali Youssef, Indrajeet Karnik, Kavish Sanil, Nagarjuna Narala, Honghe Wang, Rasha M. Elkanayati, Sateesh Kumar Vemula, Michael A. Repka   +8 more
doaj   +3 more sources