The management of schizophrenia: focus on extended-release quetiapine fumarate
Joseph Peuskens Universitair Psychiatrisch Centrum KU Leuven, Campus St Jozef Kortenberg, Kortenberg, Belgium Abstract: Effective management of schizophrenia remains a significant clinical challenge.
Peuskens J
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A Case of Serotonin Syndrome Associated With Acute Quetiapine Poisoning [PDF]
A 21-year-old woman was admitted to our emergency department following a 3-h loss of consciousness after intentional ingestion of multiple psychotropic medications.
Dan Wu, Haidong Qin
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Effect of Polymers and Permeation Enhancers in the Release of Quetiapine Fumarate Transdermal Patch through the Dialysis Membrane [PDF]
Quetiapine Fumarate is potent, and the daily therapeutic dose can be delivered easily across the skin with the help of permeation enhancers. Quetiapine Fumarate-loaded transdermal patches were prepared by solvent evaporation technique.
Mullaicharam Bhupathyraaj +2 more
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Validation of Quetiapine Fumarate in Pharmaceutical Dosage by Reverse-Phase HPLC with Internal Standard Method [PDF]
A rapid, specific, and accurate isocratic HPLC method was developed and validated for the assay of quetiapine fumarate in pharmaceutical dosage forms. The assay involved an isocratic-elution of quetiapine fumarate in Grace C18 column using mobile-phase ...
Kiran B. Venkata +2 more
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In-vivo study of quetiapine fumarate superporous hydrogels
This study aims to design and evaluate a gastroretentive drug delivery system using second generation Superporous hydrogels using Factorial design approach. Optimized formulation was assessed for pharmacokinetic parameters by In-vivo study. Pharmacokinetic analysis of Quetiapine Fumarate plasma concentration–time data provided the following ...
Chelikani Ram Venkatesh +1 more
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Tablet Splitting in Elderly Patients with Dementia: The Case of Quetiapine [PDF]
Quetiapine is an atypical antipsychotic approved for treating schizophrenia, bipolar depression, and mania but is frequently used in an off-label manner to control the behavioral and psychological symptoms of dementia in elderly patients with dementia ...
Roberta Ganzetti +7 more
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Hemodialysis Treatment for High-Dose Quetiapine Fumarate Poisoning: A Case Report [PDF]
Introduction: Quetiapine is a new atypical antipsychotic with minor side effects. There have been few reports of rhabdomyolysis and acute kidney injury associated with quetiapine overdose.
Jiaoyang Li +3 more
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Post‐marketing surveillance of quetiapine fumarate extended‐release tablets in patients with bipolar depression [PDF]
Aim This study aimed to verify the real‐world efficacy and safety of quetiapine fumarate extended‐release tablets (Bipresso® 50 mg and 150 mg; marketing authorization holder is KYOWA Pharmaceutical Industry Co., Ltd., Osaka, Japan) in patients with ...
Taro Kishi +3 more
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Formulation and Evaluation of Gastroretentive Floating Tablets of Quetiapine Fumarate
The objective of the present study was to develop gastroretentive floating tablets of quetiapine fumarate. The gastroretentive floating tablets of quetiapine fumarate were formulated using natrosol 250 HHX as a sustained release polymer and sodium bicarbonate as a gas forming agents.
Advaita B. Patel +4 more
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Formulation Development of Solid Self-Nanoemulsifying Drug Delivery Systems of Quetiapine Fumarate via Hot-Melt Extrusion Technology: Optimization Using Central Composite Design [PDF]
Quetiapine fumarate (QTF) was approved for the treatment of schizophrenia and acute manic episodes. QTF can also be used as an adjunctive treatment for major depressive disorders. QTF oral bioavailability is limited due to its poor aqueous solubility and
Prateek Uttreja +8 more
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