Influence of Plasdone™ S630 Ultra-an Improved Copovidone on the Processability and Oxidative Degradation of Quetiapine Fumarate Amorphous Solid Dispersions Prepared via Hot-Melt Extrusion Technique. [PDF]
AAPS PharmSciTech, 2021 In a formulation, traces of peroxides in copovidone can impact the stability of drug substances that are prone to oxidation. The present study aimed to investigate the impact of peroxides in novel Plasdone™ S630 Ultra and compare it with regular Plasdone™
Butreddy A +8 more
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Pharmacokinetic evaluation of quetiapine fumarate controlled release hybrid hydrogel: a healthier treatment of schizophrenia [PDF]
Drug Delivery, 2018 The current study aimed to rationally develop and characterize pH-sensitive controlled release hydrogels by graft polymerization of gelatin (Gel) and hydroxypropyl methyl cellulose (HPMC) in the presence of glutaraldehyde (GA) using quetiapine fumarate ...
Muhammad Akhlaq +10 more
doaj +2 more sources
Journal of Applied Pharmaceutical ResearchBackground: Quetiapine fumarate (QTF) is a high-affinity monoaminergic antagonist selective for serotonin Type 2 (5HT2) and dopamine Type 2 (D2) receptors.
Aakanksha Sinha, S J Daharwal
doaj +2 more sources
Ars PharmaceuticaIntroduction: Quetiapine Fumarate (QF) is a second-generation antipsychotic used to treat schizophrenia and bipolar depression. Extended-release (ER) tablets help improve patient compliance and reduce side effects by slowing down drug absorption. Method:
Subhalakshmi Muruganantham +2 more
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Bulletin of Faculty of Pharmacy Cairo University, 2018 The present work aims to discuss on Quality by Design based development and characterization of the sustained release mucoadhesive microspheres of quetiapine fumarate. The microspheres were prepared by non-aqueous solvent evaporation process.
Someshwar Komati +5 more
doaj +2 more sources
Formulation and evaluation of buccoadhesive quetiapine fumarate tablets [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2012 The aim of present study was to develop and evaluate buccoadhesive Quetiapine Fumarate (QF) tablets, which is extensively metabolised by liver. Buccoadhesive tablets of QF were prepared using HPMC K4M, HPMC K15M and combination of carbopol and HPC as ...
Appa Rao Potu +3 more
doaj +4 more sources
Formulation and Evaluation of Gastroretentive Floating Tablets of Quetiapine Fumarate
Journal of Drug Delivery and Therapeutics, 2021 The objective of the present study was to develop gastroretentive floating tablets of quetiapine fumarate. The gastroretentive floating tablets of quetiapine fumarate were formulated using natrosol 250 HHX as a sustained release polymer and sodium ...
Keyur S. Patel +4 more
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EXTRACTIVE SPECTROPHOTOMETRIC DETERMINATION OF QUETIAPINE FUMARATE IN PHARMACEUTICALS AND HUMAN URINE USING CALMAGITE AS AN ION-PAIR REAGENT [PDF]
Chemical Industry and Chemical Engineering Quarterly, 2011 Quetiapine fumarate (QTF) is an antipsychotic drug belonging to the benzisoxazole derivatives indicated for the treatment of schizophrenia. A sensitive and selective method based on dichloromethane-extractable ion-pair of QTF with calmagite (CGT), which ...
NAGARAJU RAJENDRAPRASAD +2 more
doaj +3 more sources
Quetiapine fumarate augmentation for patients with a primary anxiety disorder or a mood disorder: a pilot study [PDF]
BMC Psychiatry, 2012 Background Comorbid anxiety symptoms,in patients with a primary anxiety disorder or a mood disorder, leads to poor patient outcomes and burdens the healthcare system.
Chen Yi-Chih +2 more
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Optimization and evaluation of modified release solid dosage forms using artificial neural network [PDF]
Scientific ReportsThis study aims to optimize and evaluate drug release kinetics of Modified-Release (MR) solid dosage form of Quetiapine Fumarate MR tablets by using the Artificial Neural Networks (ANNs).
Tulsi Sagar Sheth, Falguni Acharya
doaj +2 more sources