SOLUBILITY AND THERMODYNAMIC MODELING OF QUETIAPINE FUMARATE IN SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS) [PDF]
Objective: The present study gives emphasis on the development of self-nanoemulsifying drug delivery system (SNEDDS) of poorly water-soluble drug using Apelblat model.
Swati G. Talele, Deelip V. Derle
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A simple, sensitive, rapid, robust and reproducible method for the determination of Quetiapine fumarate in bulk and pharmaceutical formulation (Tablets) was developed using reverse phase high performance liquid chromatographic method (RP-HPLC).
Nikita Garhewal +2 more
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Formulation and pharmaceutical development of quetiapine fumarate sustained release matrix tablets using a QbD approach [PDF]
The main objective of the present study was to apply QbD methodology in the development of once-a-day sustained release quetiapine tablets. The quality target product profile (QTPP) was defined after the pharmaceutical properties and kinetic release of ...
Gavan Alexandru +3 more
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In vitro and in vivo evaluation of Quetiapine fumarate controlled gastroretentive floating drug delivery system [PDF]
The aim of the present work was to develop and optimize gastroretentive floating system of Quetiapine fumarate (QF) for the effective treatment of Schizophrenia. The present study was carried out with an objective of preparation and in vivo evaluation of
A. Kishore Babu, M. Venkata Ramana
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Impact of hydrophilic binders on stability of lipid-based sustained release matrices of quetiapine fumarate by the continuous twin screw melt granulation technique. [PDF]
Nyavanandi D +6 more
europepmc +2 more sources
Formulation Development and Characterization of Pullulan Based Quetiapine Fumarate Oral Films
Quetiapine fumarate is one of the major FDA approved drug in treatment of schizophrenia. Since this drug was having very low bioavailability of 9% and extensive metabolism in liver, it was selected as a suitable drug candidate for our study.
Venu Babu Chennupati +1 more
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Quality by Design Approach for Development and Characterisation of Solid Lipid Nanoparticles of Quetiapine Fumarate. [PDF]
Agarwal S +3 more
europepmc +3 more sources
Background Lithium and several atypical antipsychotics are the recommended first-line augmentation options for treatment-resistant depression; however, few studies have compared them directly, and none for longer than 8 weeks.
Jess Kerr-Gaffney +14 more
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Coma After Quetiapine Fumarate Intentional Overdose in a 71-year-old Man: A Case Report. [PDF]
Gibiino S +4 more
europepmc +3 more sources
Dependence on zopiclone: a case report [PDF]
BackgroundZopiclone, a cyclopyrrolone derivative, is commonly employed for the short-term treatment of different types of insomnia. In comparison to benzodiazepines, Zopiclone appears to have a lower risk of abuse potential and withdrawal symptoms ...
Nana Guo +3 more
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