Results 31 to 40 of about 38,240 (235)

SOLUBILITY AND THERMODYNAMIC MODELING OF QUETIAPINE FUMARATE IN SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS) [PDF]

open access: diamond, 2018
Objective: The present study gives emphasis on the development of self-nanoemulsifying drug delivery system (SNEDDS) of poorly water-soluble drug using Apelblat model.
Swati G. Talele, Deelip V. Derle
openalex   +5 more sources

Development and Validation of Assay Method for Determination of Quetiapine Fumarate by RP-HPLC from Bulk and Pharmaceutical Dosage Form

open access: diamondInternational journal of pharmaceutical sciences and medicine, 2022
A simple, sensitive, rapid, robust and reproducible method for the determination of Quetiapine fumarate in bulk and pharmaceutical formulation (Tablets) was developed using reverse phase high performance liquid chromatographic method (RP-HPLC).
Nikita Garhewal   +2 more
openalex   +2 more sources

Formulation and pharmaceutical development of quetiapine fumarate sustained release matrix tablets using a QbD approach [PDF]

open access: yesActa Pharmaceutica, 2017
The main objective of the present study was to apply QbD methodology in the development of once-a-day sustained release quetiapine tablets. The quality target product profile (QTPP) was defined after the pharmaceutical properties and kinetic release of ...
Gavan Alexandru   +3 more
doaj   +3 more sources

In vitro and in vivo evaluation of Quetiapine fumarate controlled gastroretentive floating drug delivery system [PDF]

open access: gold, 2016
The aim of the present work was to develop and optimize gastroretentive floating system of Quetiapine fumarate (QF) for the effective treatment of Schizophrenia. The present study was carried out with an objective of preparation and in vivo evaluation of
A. Kishore Babu, M. Venkata Ramana
openalex   +3 more sources

Formulation Development and Characterization of Pullulan Based Quetiapine Fumarate Oral Films

open access: bronzeInternational Journal of Drug Delivery Technology
Quetiapine fumarate is one of the major FDA approved drug in treatment of schizophrenia. Since this drug was having very low bioavailability of 9% and extensive metabolism in liver, it was selected as a suitable drug candidate for our study.
Venu Babu Chennupati   +1 more
openalex   +2 more sources

Clinical and cost-effectiveness of lithium versus quetiapine augmentation for treatment-resistant depression in adults: LQD a pragmatic randomised controlled trial

open access: yesHealth Technology Assessment
Background Lithium and several atypical antipsychotics are the recommended first-line augmentation options for treatment-resistant depression; however, few studies have compared them directly, and none for longer than 8 weeks.
Jess Kerr-Gaffney   +14 more
doaj   +2 more sources

Dependence on zopiclone: a case report [PDF]

open access: yesFrontiers in Psychiatry
BackgroundZopiclone, a cyclopyrrolone derivative, is commonly employed for the short-term treatment of different types of insomnia. In comparison to benzodiazepines, Zopiclone appears to have a lower risk of abuse potential and withdrawal symptoms ...
Nana Guo   +3 more
doaj   +2 more sources

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