Neutrophil to lymphocyte ratio as a predictor of response to neoadjuvant chemotherapy and survival in oesophageal adenocarcinoma [PDF]
Background Inflammation has an important role in cancer survival, yet whether serum markers of inflammation predict response to potentially curative neoadjuvant chemotherapy (NAC) in oesophageal adenocarcinoma (OAC) is controversial.
A. G. M. T. Powell +6 more
doaj +3 more sources
Quimioterapia neoadyuvante en cáncer de mama, localmente avanzado
Introducción: el cáncer de mama es actualmente el tumor maligno más frecuente en la mujer y la quimioterapia constituye una de las principales armas terapéuticas en este padecimiento. Objetivo: caracterizar el comportamiento de los enfermos con cáncer
Alexander Portelles Cruz +4 more
doaj +1 more source
HER2-low y respuesta a la quimioterapia neoadyuvante en cáncer de mama temprano
Introducción: el cáncer de mama es la primera causa de muerte por cáncer entre las mujeres. Los tumores HER2-low tienen una baja expresión de HER2 estimándose que la proporción está entre el 45%-55%. Análisis de cohortes no apoyan la interpretación que el cáncer de mama HER2-low como un subtipo biológico distinto.
Alfredo Sebastian Golemba +3 more
openaire +2 more sources
Impact on postoperative complications of changes in skeletal muscle mass during neoadjuvant chemotherapy for gastro-oesophageal cancer. [PDF]
Deconditioning during neoadjuvant chemotherapy is a possible parameter for predicting operative outcomes. This retrospective cohort study aimed to assess body composition changes in patients with gastro‐oesophageal cancer during neoadjuvant therapy and investigate their association with postoperative complications. Skeletal muscle index values decrease
den Boer RB +9 more
europepmc +2 more sources
Multicentre study of perioperative versus adjuvant chemotherapy for resectable colorectal liver metastases. [PDF]
This study aimed to estimate the effect of neoadjuvant FOLFOX in patients undergoing upfront resectable colorectal liver metastases. After adjustment, no significant impact of FOLFOX was detected, suggesting that upfront surgery may be acceptable in patients with limited disease.
Allard MA +16 more
europepmc +2 more sources
Propensity score regression analysis of oesophageal adenocarcinoma treatment with surgery alone or neoadjuvant chemotherapy. [PDF]
Following propensity adjustment for stage, age and sex, neoadjuvant therapy was not associated with survival. Tumour regression is a powerful prognostic indicator, and future research should focus on identifying patients who will derive the most benefit from neoadjuvant chemotherapy.
Powell AGMT +5 more
europepmc +2 more sources
Multicentre study of prepectoral breast reconstruction using acellular dermal matrix. [PDF]
A UK multicentre audit of direct‐to‐implant prepectoral breast reconstructions using acellular dermal matrix was conducted for all patients operated on from January 2015 to December 2017 across 18 centres. In a median follow‐up of 9·7 months, the major complication rate was 15·3 per cent and the 90‐day implant removal rate 4·9 per cent.
Chandarana M +2 more
europepmc +2 more sources
Antecedentes. El uso de quimioterapia neoadyuvante (QTN) en cáncer de mama (CB) menos agresivo es controversial. Objetivo: Investigar el efecto de la quimioterapia neoadyuvante en el cáncer de mama HER2 negativo luminal B. Método.
Aysegul Aktas +4 more
doaj +1 more source
Introducción: las antraciclinas han sido uno de los estándares de manejo en quimioterapia en cáncer de mama Her2 positivo desde la enfermedad temprana como metastásica, sin embargo, su riesgo de cardiotoxicidad irreversible es uno de los principales ...
Javier Cuello López +3 more
semanticscholar +2 more sources
Prediction of a positive circumferential resection margin at surgery following neoadjuvant chemotherapy for adenocarcinoma of the oesophagus. [PDF]
A positive circumferential resection margin (CRM) has been shown to be an adverse prognostic indicator after oesophagectomy for adenocarcinoma. Clinical tumour status, tumour volume, poor differentiation, lack of response following chemotherapy and radiological assessment of invasion can be used to predict CRM positivity in oesophageal adenocarcinoma ...
Knight WRC +30 more
europepmc +2 more sources

