Impact on postoperative complications of changes in skeletal muscle mass during neoadjuvant chemotherapy for gastro-oesophageal cancer. [PDF]
Deconditioning during neoadjuvant chemotherapy is a possible parameter for predicting operative outcomes. This retrospective cohort study aimed to assess body composition changes in patients with gastro‐oesophageal cancer during neoadjuvant therapy and investigate their association with postoperative complications. Skeletal muscle index values decrease
den Boer RB +9 more
europepmc +2 more sources
Neutrophil to lymphocyte ratio as a predictor of response to neoadjuvant chemotherapy and survival in oesophageal adenocarcinoma. [PDF]
The neutrophil to lymphocyte ratio, dichotomized at 2·25, was strongly associated with Mandard tumour regression grade in patients who had neoadjuvant chemotherapy for oesophageal adenocarcinoma. The systemic inflammatory response may offer a novel therapeutic target for patients at risk of poor response.
Powell AGMT +6 more
europepmc +2 more sources
Multicentre study of perioperative versus adjuvant chemotherapy for resectable colorectal liver metastases. [PDF]
This study aimed to estimate the effect of neoadjuvant FOLFOX in patients undergoing upfront resectable colorectal liver metastases. After adjustment, no significant impact of FOLFOX was detected, suggesting that upfront surgery may be acceptable in patients with limited disease.
Allard MA +16 more
europepmc +2 more sources
Prediction of a positive circumferential resection margin at surgery following neoadjuvant chemotherapy for adenocarcinoma of the oesophagus. [PDF]
A positive circumferential resection margin (CRM) has been shown to be an adverse prognostic indicator after oesophagectomy for adenocarcinoma. Clinical tumour status, tumour volume, poor differentiation, lack of response following chemotherapy and radiological assessment of invasion can be used to predict CRM positivity in oesophageal adenocarcinoma ...
Knight WRC +30 more
europepmc +2 more sources
Quimioterapia neoadyuvante en cáncer de mama, localmente avanzado
Introducción: el cáncer de mama es actualmente el tumor maligno más frecuente en la mujer y la quimioterapia constituye una de las principales armas terapéuticas en este padecimiento. Objetivo: caracterizar el comportamiento de los enfermos con cáncer
Alexander Portelles Cruz +4 more
doaj +1 more source
Tumor response to neoadjuvant chemotherapy in molecular breast cancer subtypes in Medellin, Colombia. Retrospective cohort study [PDF]
Objetivos: describir la frecuencia de la respuesta clínica y patológica, entre los diferentes subtipos moleculares de cáncer de mama, en pacientes que previamente recibieron quimioterapia neoadyuvante.
Restrepo-Mejía M +4 more
europepmc +2 more sources
Complete pathological response in patients with HER2 positive breast cancer treated with neoadjuvant therapy in Colombia [PDF]
Introduction. Breast cancer is the most common type of cancer and the leading cause of death by cancer in women in Colombia. Approximately 15 to 20% of breast cancers overexpress HER2. Objective.
Rodríguez M +4 more
europepmc +2 more sources
Antecedentes. El uso de quimioterapia neoadyuvante (QTN) en cáncer de mama (CB) menos agresivo es controversial. Objetivo: Investigar el efecto de la quimioterapia neoadyuvante en el cáncer de mama HER2 negativo luminal B. Método.
Aysegul Aktas +4 more
doaj +1 more source
Introducción: La biopsia selectiva del ganglio centinela (BSGC) en cáncer de mama es el método estándar para estadificación axilar en pacientes con axila clínicamente negativa.
Carlos Humberto Malatay González +3 more
doaj +1 more source
Últimos avances en el tratamiento neoadyuvante de cáncer de vejiga
La quimioterapia neoadyuvante basada en cisplatino ha demostrado un claro beneficio en cáncer de vejiga músculo invasivo (MIBC) EC II o IIIA, logrando un impacto en la sobrevida libre de progresión y sobrevida global. Esta revisión actualizada se centra
Patricia Rioja +6 more
doaj +1 more source

