Results 161 to 170 of about 11,113 (225)

Development of synthetic chloride transporters using high-throughput screening and machine learning. [PDF]

Digit Discov
Chowdhury SM, Daood NJ, Lewis KR, Salam R, Zhu H, Busschaert N.   +5 more
europepmc   +1 more source

Redefining Breast Cancer Care by Harnessing Computational Drug Repositioning. [PDF]

Medicina (Kaunas)
Jurj ED, Colibășanu D, Vasii SO, Suciu L, Dehelean CA, Udrescu L.   +5 more
europepmc   +1 more source

Mouse germline cysts contain a fusome-like structure that mediates oocyte development. [PDF]

Elife
Pathak M, Spradling AC.
europepmc   +1 more source

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Iodoquinol and Quinacrine

2010
Iodoquinol and quinacrine are luminal antiprotozoal agents that have activity against Entamoeba histolytica and Giardia lamblia, respectively, but are now rarely used in most settings because of the availability of other, more active and less toxic agents.
Pollard, James, McCarthy, James
openaire   +2 more sources

Quinacrine is a prostaglandin antagonist

Biochemical and Biophysical Research Communications, 1977
Abstract Quinacrine, an anti-malarial with local anaesthetic properties, because of its fluorescence characteristics and its ability to combine with chromosomes and biological membranes has been widely used as a “probe”. The sites with which it combines in Torpedo marmorata electric organs have many of the characteristics of specific receptors.
D F, Horrobin, M S, Manku, M, Karmazyn, A I, Ally, R O, Morgan, R A, Karmali   +5 more
openaire   +2 more sources

Quinacrine sterilization: a retrospective

International Journal of Gynecology & Obstetrics, 2003
AbstractObjective: To trace development of quinacrine sterilization (QS). Methods: Review of published reports. Results: The high prevalence of septic abortion among high parity women in Santiago, Chile, motivated Zipper to find a safe, inexpensive method of non‐surgical female sterilization. Various cytotoxic drugs were tried in rats.
J, Zipper, E, Kessel
openaire   +3 more sources

Assay of Quinacrine Hydrochloride

Journal of Pharmaceutical Sciences, 1969
Comparison of USP method for the assay of quinacrine hydrochloride involving precipitation of the dichromate salt and determination of the excess dichromate with the nonaqueous titration using a visual end point and a proposed nonaqueous titration with a potentiometric end point, shows that all three methods give the same results, with the nonaqueous ...
I S, Gibbs, M M, Tuckerman
openaire   +2 more sources

Sterilant Action of Quinacrine

Fertility and Sterility, 1977
A question concerning the mode of action and degree of effectiveness of the chemosterilant quinacrine for achieving tubal occlusion for sterilization in women is posed. Quinacrine acts as a powerful obstructive agent exclusively on the epithelium of the intramural portion of the tube without altering the histology of the endometrium.
openaire   +2 more sources

Quinacrine-Induced Psychiatric Disturbances

Southern Medical Journal, 1982
We have described three patients who illustrate the broad clinical spectrum of quinacrine-associated neuropsychiatric disturbances. The toxic manifestations range from subtle changes of restlessness, insomnia, hyperirritability to frank psychosis and seizures. These symptoms may follow only a few doses of the drug, or they may occur well after the drug
S J, Weisholtz, P A, McBride, H W, Murray, M K, Shear   +3 more
openaire   +2 more sources

TREATMENT OF TENIASIS WITH QUINACRINE HYDROCHLORIDE

JAMA: The Journal of the American Medical Association, 1952
In 1940 Culbertson 1 reported the successful action of quinacrine hydrochloride (atabrine® dihydrochloride) in the elimination of the tapeworm Hymenolepis fraterna from mice. He described the ready penetration of the wall of the small intestine by the drug, particularly in areas where the parasite is found. Later, in 1946, Saccomanno 2 reported the use
W A, SODEMAN, R C, JUNG
openaire   +2 more sources