Results 171 to 180 of about 11,113 (225)

100 000 quinacrine sterilizations

Advances in Contraception, 1996
100000 quinacrine nonsurgical female sterilizations have been completed over the past decade involving transcervical insertion of quinacrine (252 mg) as pellets by one, two or three monthly insertions. No deaths have been reported and serious complications are far fewer than for surgical sterilization. Side-effects are mild and transient.
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Quinacrine

2000
Abstract Quinacrine is an acridone derivative used as an intestinal anthelmintic and as an antimalarial; it is also frequently utilized for treatment of giardiasis, and its suitability as a female sterilization agent has been suggested. Veterinary uses include antiprotozoal and taeniacide treatment (9). The drug is no longer available
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Action of quinacrine mustard on polynucleotides

Biochimie, 1972
Summary Treatment of nucleic acids and synthetic polynucleotides with quinacrine mustard gives polymers with a covalently bound fluorescent marker. All the natural bases can react but adenine and guanine are attacked preferentially under the conditions used.
A M, Michelson, C, Monny, A, Kovoor
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Quinacrine Fluorescence in Mammalian Chromosomes

Nature, 1971
SINCE the possibilities of revealing chromosomal structure by staining chromatin with dyes derived from acridine first became apparent1, we have used the antimalarial compound quinacrine dihydrochloride (‘Atebrin’, G. Gurr Ltd) to study the highly fluorescent area on the long arms of the human Y chromosome and in localized regions of certain autosomes2–
P L, Pearson, M, Bobrow, C G, Vosa, P W, Barlow   +3 more
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Ochronosis from Quinacrine (Atabrine)

Annals of Internal Medicine, 1963
Excerpt Ochronosis is usually associated with the rare hereditary metabolic disease, alcaptonuria, in which there is a defect in the hepatic enzyme, homogentisic acid oxidase, and consequently an a...
G D, LUDWIG, J F, TOOLE, J C, WOOD
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Quinacrine (Atebrin): Mode of Action

Science, 1967
Quinacrine at a concentration of 8 × 10 -4 mole per liter is bactericidal for Escherichia coli , blocks DNA synthesis, and inhibits the syntheses of RNA and protein strongly. At a concentration of 2 × 10 -4 mole per liter, the drug is bacteriostatic, the syntheses of ...
J, Ciak, F E, Hahn
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The distribution of quinacrine in Taenia saginata

Experimental Parasitology, 1954
Abstract The distribution of quinacrine in six beef tapeworms, Taenia saginata , expelled by this drug has been studied with the aid of a fluorescent microscope. The observation that quinacrine possesses a great affinity for the holdfast organs may be of value in explaining the teniafugal action of quinacrine.
K K, MUSTAKALLIO, J I, SAIKKONEN
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Quinacrine sterilization in Tripura, India

Contraception, 2001
A 611-case clinical trial of quinacrine sterilization (QS) was conducted at Agartala, Tripura State, India, using a unique protocol. No pregnancy failures were reported after a mean of 45.8 months of follow-up. Three trans-cervical insertions of 324 mg, 288 mg, and 252 mg quinacrine pellets were used in the first, second, and third insertions ...
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Quinacrine sterilization: a middle road

Contraception, 2001
Discussion of female sterilization using the trans-cervical application of quinacrine hydrochloride (quinacrine sterilization; QS) has become highly polarized [1,2]. We feel the unreasoned passion about QS is making evidence-based decisions difficult to reach.
M, Potts, G, Benagiano
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DERMATITIS DUE TO QUINACRINE HYDROCHLORIDE

Archives of Dermatology, 1946
T HE presence of our troops in strength in the regions of endemic malaria in the Southwest Pacific has presented opportunity for the extensive clinical use of quinacrine hydrochloride, U. S. P. (atabrine). Its use as a suppressive agent has been enthusiastically described in lay and scientific literature.
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