Results 151 to 160 of about 49,957 (191)
Synthesis, Antibacterial Properties and Molecular Docking Studies of Nitrogen Substituted 9-(((4X-But-2-ynyloxy)methyl)-1,2,3-triazolyl)-Cinchona Alkaloid Conjugates. [PDF]
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Naunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie, 1948
Studies of the comparative pharmacology of quinine revealed that rabbits possessed an unusual ability to metabolize this drug. The metabolic derivative formed by rabbit liver in vitro was isolated in pure crystalline form and found to possess a lower toxicity and antimalarial activity than quinine.
E M K, GEILING, F E, KELSEY
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Studies of the comparative pharmacology of quinine revealed that rabbits possessed an unusual ability to metabolize this drug. The metabolic derivative formed by rabbit liver in vitro was isolated in pure crystalline form and found to possess a lower toxicity and antimalarial activity than quinine.
E M K, GEILING, F E, KELSEY
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1984
Quinine, the oldest universally known antimalarial agent, has been the subject of numerous reviews in the past. We do not intend in this chapter to repeat once more all the known facts about quinine, but rather to select and critically discuss those properties which are essential for an assessment of its merits and its defaults in comparison with its ...
W. Hofheinz, B. Merkli
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Quinine, the oldest universally known antimalarial agent, has been the subject of numerous reviews in the past. We do not intend in this chapter to repeat once more all the known facts about quinine, but rather to select and critically discuss those properties which are essential for an assessment of its merits and its defaults in comparison with its ...
W. Hofheinz, B. Merkli
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Journal of Antimicrobial Chemotherapy, 1992
Quinine, an alkaloid derived from the bark of the cinchona tree was brought to Europe from Peru in the 17th century. Isolation of quinine and other cinchona alkaloids was achieved in France in the early part of the 19th century and uncertainties of supply of the bark stimulated efforts to synthesize quinine.
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Quinine, an alkaloid derived from the bark of the cinchona tree was brought to Europe from Peru in the 17th century. Isolation of quinine and other cinchona alkaloids was achieved in France in the early part of the 19th century and uncertainties of supply of the bark stimulated efforts to synthesize quinine.
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2010
The cinchona alkaloid quinine and its d-diastereomer quinidine have been used for over 350 years for the treatment of malaria (Rocco, 2003). Although the bark of the cinchona tree had been used as a traditional medicine for the relief of fever by Andean healers, it was first used in Europe for ague (malaria) in the 17th century by Cardinal Juan de Lugo,
Hajkowicz, Krispin M., Cheng, Allen C.
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The cinchona alkaloid quinine and its d-diastereomer quinidine have been used for over 350 years for the treatment of malaria (Rocco, 2003). Although the bark of the cinchona tree had been used as a traditional medicine for the relief of fever by Andean healers, it was first used in Europe for ague (malaria) in the 17th century by Cardinal Juan de Lugo,
Hajkowicz, Krispin M., Cheng, Allen C.
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Medicine, 2003
Abstract Quinine and chloroquine are the most common antimalarial drugs encountered in acute poisoning. Their severe toxicity in overdose results from cardiotoxicity secondary to membrane-stabilizing effects.
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Abstract Quinine and chloroquine are the most common antimalarial drugs encountered in acute poisoning. Their severe toxicity in overdose results from cardiotoxicity secondary to membrane-stabilizing effects.
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