Results 171 to 180 of about 82,349 (282)

Extracting Mechanistic Information from an Open Data Set for a Pharma-Relevant Suzuki-Miyaura Cross-Coupling Reaction. [PDF]

Org Process Res Dev
Franklin BA, Donaldson NWB, Firth JD, Horbaczewskyj CS, Aspell A, Tanner T, Whitwood AC, Wilson J, Hargreaves JK, Fairlamb IJS.   +9 more
europepmc   +1 more source

Global consensus on the management of melanin hyperpigmentation disorders

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 760-772, May 2026.
A global Delphi consensus of 10 dermatology experts established evidence‐based recommendations for melanin hyperpigmentation disorders, providing unified classification, photoprotection guidance and treatment algorithms. This framework harmonizes terminology and supports individualized management across diverse skin types and health systems.
Thierry Passeron, Seemal R. Desai, Marwa Abdallah, Firas Al‐Niaimi, Ncoza Dlova, Pearl E. Grimes, Jorge Ocampo‐Candiani, Rashmi Sarkar, Leihong Flora Xiang, Helio Amante Miot   +9 more
wiley   +1 more source

Photoenzymatic Hydroalkylation Enables Streamlined Access to Aryl Glutarimide Precursors

Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.
We report a photoenzymatic hydroalkylation that enables streamlined, stereocontrolled access to aryl glutarimide precursors relevant to targeted protein degradation. Engineered flavin‐dependent “ene”‐reductases provide broad scope and high enantioselectivity through a distinct electron transfer–enantioselective proton transfer pathway.
Zhi Xu, Prasun Mukherjee, Steven Gossert, Stephen Thomas, Vasil H. Vasilev, Eric R. Welin, Yichen Tan, Shane M. McKenna, Megan A. Emmanuel, Todd K. Hyster   +9 more
wiley   +2 more sources

Turn-on quinoline probe for selective sensing of hypochlorite in live cells. [PDF]

Sci Rep
Olubiyo FF, Klu SYS, Burgess RJ, Hou Y.
europepmc   +1 more source

Tomato Spotted Wilt Virus Reprogrammes Host Glycolysis to Facilitate Proliferation by a Phase‐Separated Co‐Aggregate of Nucleocapsid Protein and Phosphoglycerate Kinase

Plant Biotechnology Journal, Volume 24, Issue 5, Page 2826-2842, May 2026.
ABSTRACT Efficient viral proliferation within the host is a critical step in pathogenicity and requires adenosine triphosphate (ATP). The replication, movement and immune evasion of many plant viruses within their hosts are associated with phase separation (PS)‐derived aggregates formed by viral components.
Guangcheng Zu, Zhifu Xing, Jiao Li, Tangbing Yang, Huan Wu, Qiangsheng Ge, Yanju Wang, Baoan Song, Runjiang Song   +8 more
wiley   +1 more source

Derivatization agents for LC-MS analysis of amino acids: effects of core structure and functional groups. [PDF]

Anal Bioanal Chem
Hofmanova T, Andrys R, Lisa M.
europepmc   +1 more source

Discovery of [1,2,4]triazolo[1,5‐a]pyrimidine‐Imatinib Hybrids With Selective Cytotoxic Activity: A Mechanistically Divergent Series From Direct BCR‐ABL1 Inhibition

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
Discovery of imatinib–triazolopyrimidine hybrids with selective cytotoxicity and a mechanism distinct from classical BCR‐ABL1 inhibition. This bioisosteric strategy introduces a novel compounds, paving the way for innovative antileukemic therapies with differentiated profiles.
Stefany Castro Bazan Moura, Andressa Paula de Oliveira, Joao de Mello Rezende Neto, Rafael Ferreira Dantas, Floriano Paes Silva‐Jr, Luiz Claudio Pimentel, Mayara Salles do Nascimento Carvalho, Debora Inacio Leite, Daiane Vitoria da Silva, Monica Macedo Bastos, Nubia Boechat   +10 more
wiley   +1 more source

Efficient one-pot quinoline derivative synthesis from acetophenone and allyl alcohols. [PDF]

RSC Adv
Zeng F, Xu Y, Fang J, Xu H, Cai Y, Hong Y, Gao J, Zeng Q, Su X.   +8 more
europepmc   +1 more source

Unveiling the Photophysical Properties of Indole‐Containing Boron Complexes: Exploring Intramolecular Charge Transfer Character, Tunable Emission, and Large Stokes Shifts

ChemPhysChem, Volume 27, Issue 8, 28 April 2026.
Indolyl‐imine–based NN complexes were synthesized and investigated to clarify how structural modification tunes intramolecular charge transfer (ICT), resulting in large Stokes shifts and tunable emission properties. Steady‐state and ultrafast spectroscopy, supported by density‐functional theory (DFT), showed that altering peripheral phenyl groups ...
Emrah Özcan, Valentyna Kuznetsova, Alina Kaliuzhna, Zehra Coşkun, Mehmet F. Saglam, Ibrahim F. Sengul, Fahri Alkan, Tomas Polivka, Bünyemin Çoşut   +8 more
wiley   +1 more source

Chalcogen substitution and ionization effects on the fluorescence behavior of 8-chalcogen-quinoline-BODIPY: a DFT and TD-DFT investigation. [PDF]

RSC Adv
Bay MV, Vo QV, Trung NQ, Nam NL, Nam PC, Thong NM.   +5 more
europepmc   +1 more source