Results 201 to 210 of about 82,349 (282)

From Synthesis to Mechanism: Biological Evaluation of a p-Toluidine-Based Thiazolidinone-Quinoline VEGFR-2 Candidate Supported by CADD. [PDF]

Int J Mol Sci
Manni E, Hussein MF, Elkady S, Abdel-Rahman AA, Hawata MA, El-Sayed WA, El-Sayed AF, El-Hema HS.   +7 more
europepmc   +1 more source

2‐Phenylquinolines Exhibit Anti‐Severe Acute Respiratory Syndrome Coronavirus‐2 Activity Through the Nonstructural Protein 13 Helicase Inhibition

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
A SAR study led to the identification of new 2‐phenylquinoline‐based derivatives that exhibit anti‐Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) activity by acting as ATP‐competitive inhibitors of nonstructural protein 13 (nsp13) helicase.
Giada Cernicchi, Maria Giulia Nizi, Roberta Emmolo, Leentje Persoons, Manon Laporte, Dirk Jochmans, Isabella Romeo, Giacomo Pepe, Ciro Milite, Pietro Campiglia, Jacopo Spezzini, Alma Martelli, Simone Brogi, Francesca Esposito, Tommaso Felicetti, Serena Massari, Giuseppe Manfroni, Stefano Sabatini, Gianluca Sbardella, Stefano Alcaro, Johan Neyts, Angela Corona, Enzo Tramontano, Steven De Jonghe, Oriana Tabarrini   +24 more
wiley   +1 more source

Scalable Access to N‑Acylindole Linkages: Enabling the Synthesis of Antitrypanosomal Noncanonical Cyclic Peptides for Chagas Disease

Angewandte Chemie, Volume 138, Issue 15, 6 April 2026.
A gram‐scale supply of bulbiferamide A, which features a rare N‐acylindole linkage and possesses potent inhibitory activity against Trypanosoma cruzi epimastigotes (IC50 = 4.1 µM)—the causative parasite of Chagas disease—was successfully achieved. Moreover, the cyclization strategy developed in this study facilitated the synthesis of noncanonical ...
Jie Zhang, Hugh Nakamura
wiley   +2 more sources

Synthesis of Novel Arylhydrazones Bearing 8-Trifluoromethyl Quinoline: Crystal Insights, Larvicidal Activity, ADMET Predictions, and Molecular Docking Studies. [PDF]

Pharmaceuticals (Basel)
Kotyan S, Chandana SN, Ganesha DP, Lakshminarayana BN, Pandikatte N, Deb PK, Ghosh M, Gleiser RM, Mahomoodally MF, Alherz SA, Morsy MA, Khalil HE, Attimarad M, Nagaraja S, Almuqbil RM, Balgoname AA, Al-Dhubiab BE, Asif AH, Venugopala KN, Dasappa JP.   +19 more
europepmc   +1 more source

Simple s-block metal hydrides for selective hydrogenation of quinoline compounds. [PDF]

Chem Sci
Zhang S, Wen H, Wang Q, Cai Y, Li Z, Liu L, Chang X, Guo J, Chen P.   +8 more
europepmc   +1 more source

Quinoline-Based DNA Methyltransferase Inhibitors Featuring Basic Side Chains: Design, Synthesis, and Insight in Biochemical and Anticancer Cell Properties. [PDF]

J Med Chem
Zwergel C, Lambona C, Fioravanti R, Raucci A, Fiorentino F, Nchugoua Tchieh G, Jallet C, Lacroix L, Pierrettori M, Pellegrini FR, Xiong Y, Jin J, Arimondo P, Trisciuoglio D, Mai A, Valente S.   +15 more
europepmc   +1 more source

Recent Advances in Simultaneous Desulfurization and Denitrogenation of Fuel Oil. [PDF]

Molecules
Wang J, Wang R.
europepmc   +1 more source

(Substituted-quinoline-1-yl) Methylbenzylammonium Chloride: Quaternization Reaction Process, Corrosion Inhibition Behavior, and Calculation Process. [PDF]

Molecules
Tian J, Zinatullin R, Qian J, Li Y, Kang X, Li J, Wang Y, Huang H, Xing J.   +8 more
europepmc   +1 more source

REILLY Quinoline [PDF]

Chemical & Engineering News Archive, 1949
openaire   +1 more source

Dual-pathway detoxification by <i>Dendrobium nobile</i> Lindl. Polysaccharide: concurrent suppression of bound heterocyclic amine release and heterocyclic amine-elicited cytotoxicity during gastrointestinal digestion. [PDF]

Food Chem X
Le Y, Zhang C, Xiao J, Lei H, Quan W, Zhu H, Xiong S, Sheng J, Sun P, Xu H, Xue C.   +10 more
europepmc   +1 more source