Results 201 to 210 of about 26,162 (241)

Quantum Chemistry Investigation of Linear and Nonlinear (chir)optical Properties of Oligoamide Foldamers

open access: yesChemistryEurope, Volume 4, Issue 4, April 2026.
The linear and nonlinear (chir)optical properties of four oligoamide foldamers with different donor groups are studied by means of time‐dependent density functional theory calculations. It is shown that stronger donors yield larger hyperpolarizabilities due to low‐lying charge–transfer states. The agreement with the experiments concerning the key bands
Komlanvi Sèvi Kaka   +5 more
wiley   +1 more source

Skeletal Editing from Pyridine to Aniline via C‐Insertion and N‐Isomerization

open access: yesChemistryEurope, Volume 4, Issue 4, April 2026.
A concise protocol is presented that converts pyridines into anilines by externalizing the original pyridine nitrogen at either the "ipso" or "ortho" position, which results in para or meta‐primary aniline products. A key carbene‐insertion step precedes nitrogen migration, preserving both ring size and overall structure.
Yun Luo   +3 more
wiley   +1 more source

Identification of sulfonylated indolo[1,2-a]quinolines as EGFR tyrosine kinase inhibitors. [PDF]

open access: yesRSC Adv
Phetcharawetch J   +7 more
europepmc   +1 more source

Biosynthetically‐Inspired Oxidative Cleavage Platform Enables Rapid Access to Diverse and Architecturally Complex Chemotypes From Indole Alkaloids

open access: yesChemistryEurope, Volume 4, Issue 4, April 2026.
We report a biosynthesis‐inspired ring distortion approach that involves oxidative ring cleavage, ring rearrangement, and ring expansion reactions from a diverse collection of indole alkaloids and derivatives. This chemical synthesis approach led to the synthesis of >25 distinct chemotypes from 14 indole alkaloids.
Derek A. Leas   +7 more
wiley   +1 more source

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

open access: yesChemistry – A European Journal, Volume 32, Issue 13, 1 April 2026.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source

Modular Access to Bridgehead Heterocycle‐Substituted Bicyclo[1.1.0]butanes via Late‐Stage Functionalization of Alkynylbicyclo[1.1.0]butanes

open access: yesChemistry–Methods, Volume 6, Issue 4, April 2026.
A modular late‐stage manifold exploits the embedded alkyne of alkynylbicyclo[1.1.0]butanes (ABCBs) to deliver triazole‐, isoxazole‐, free‐NH‐pyrrole, free‐NH‐pyrazole, or silacyclohexene‐decorated BCBs in a single operation. Strain‐release transformations of bicyclo[1.1.0]butanes are powerful methods for constructing four‐membered rings and bicyclo[n.1.
Yu‐Jie Li   +3 more
wiley   +1 more source

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