Results 111 to 120 of about 136,091 (317)

Rare-Earth Metal Complexes of the Antibacterial Drug Oxolinic Acid: Synthesis, Characterization, DNA/Protein Binding and Cytotoxicity Studies

Molecules, 2020
“Drug repositioning” is a current trend which proved useful in the search for new applications for existing, failed, no longer in use or abandoned drugs, particularly when addressing issues such as bacterial or cancer cells resistance to current ...
Ana-Madalina Maciuca, Alexandra-Cristina Munteanu, Mirela Mihaila, Mihaela Badea, Rodica Olar, George Mihai Nitulescu, Cristian V. A. Munteanu, Marinela Bostan, Valentina Uivarosi   +8 more
doaj   +1 more source

The bactericidal activity of moxifloxacin in patients with pulmonary tuberculosis [PDF]

, 2003
Patients in whom acid-fast bacilli smear-positive pulmonary tuberculosis was newly diagnosed were randomized to receive 400 mg moxifloxacin, 300 mg isonaizid, or 600 mg rifampin daily for 5 days. Sixteen-hour overnight sputa collections were made for the
Bongard, E, Gillespie, SH, Gosling, RD, Kanduma, EG, Morris, RW, Nyindo, M, Sam, NE, Uiso, LO   +7 more
core   +1 more source

‘Knowledge, attitudes and practices’ survey of Austrian veterinarians' antibiotic use in clinical practice

Veterinary Record, EarlyView.
Abstract Background Antimicrobial resistance (AMR) is a critical global health issue, with antimicrobial use (AMU) in veterinary medicine playing a relevant role in its emergence. This study aimed to evaluate the knowledge, attitudes and practices of Austrian veterinarians regarding AMU and AMR.
Clair L. Firth, Patricia Mayer, Annemarie Käsbohrer, Tanja Tripolt, Klemens Fuchs   +4 more
wiley   +1 more source

2002–2022 Quinolone Resistance in Escherichia coli of Swine in Mainland China: A Meta-Analysis

Veterinary Sciences
Swine have emerged as significant reservoirs of antibiotic-resistant strains and genes. To establish a sound rationale for applying quinolone antibiotics in the swine industry, a meta-analysis was performed on the resistance rate of swine-derived ...
Xuelin Long, Shujun Liu, Runmin Kang, Yue Sun, Mingyue Tian, Lijun Zhao, Changwei Lei, Hongning Wang, Xin Yang   +8 more
doaj   +1 more source

Two new 2-alkylquinolones, inhibitory to the fish skin ulcer pathogen Tenacibaculum maritimum, produced by a rhizobacterium of the genus Burkholderia sp.

Beilstein Journal of Organic Chemistry, 2018
Exploration of rhizobacteria of the genus Burkholderia as an under-tapped resource of bioactive molecules resulted in the isolation of two new antimicrobial 2-alkyl-4-quinolones.
Dandan Li, Naoya Oku, Atsumi Hasada, Masafumi Shimizu, Yasuhiro Igarashi   +4 more
doaj   +1 more source

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association   +4 more
wiley   +1 more source

Adding gentamicin to fluoroquinolone-based antimicrobial prophylaxis reduces transrectal ultrasound-guided prostate biopsy-related infection rate

Urological Science, 2016
Objective: Transrectal ultrasound-guided prostate (TRUS) biopsy is the standard method for the diagnosis of prostate cancer. Quinolone-based prophylaxis before a TRUS biopsy of the prostate is the most common regimen worldwide.
Tzuo-Yi Hsieh, Yu-Lin Kao, Shao-Chuan Wang, Wen-Jung Chen, Sung-Lang Chen   +4 more
doaj   +1 more source

The microbiota of the bilio-pancreatic system: A cohort, STROBE-compliant study [PDF]

, 2019
Background: The gut microbiota play an essential role in protecting the host against pathogenic microorganisms by modulating immunity and regulating metabolic processes.
Agrusa A., D'arpa F., Di Carlo P., Fasciana T., Giammanco A., Gulotta G., Rodolico V., Sergi C., Serra N.   +8 more
core   +1 more source

Exposure to Systemic Antimicrobials During Pregnancy and Risk of Miscarriage: A Population‐Based Registry Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To estimate miscarriage risk following gestational antimicrobial exposure while addressing biases that have affected previous studies. Design Population‐based cohort study. Setting Linkage of four nationwide registries: Medical Birth Registry of Norway (MBRN), Norwegian Prescribed Drug Registry (NorPD), Norwegian Patient Registry ...
Thomas Boissiere‐O'Neill, Marleen M. H. J. van Gelder, Hilde M. Engjom, Hedvig M. E. Nordeng   +3 more
wiley   +1 more source

Intestinal colonization due to Escherichia coli ST131: Risk factors and prevalence [PDF]

, 2018
Background Escherichia coli sequence type 131 (ST131) is a successful clonal group that has dramatically spread during the last decades and is considered an important driver for the rapid increase of quinolone resistance in E. coli.
A Talaminos, E Torres, JH Han, JR Johnson, L López-Cerero, L López-Cerero, M-H Nicolas-Chanoine, MJ Burgess, P Huizinga, R Banerjee, V Leflon-Guibout   +10 more
core   +1 more source