Results 91 to 100 of about 71,327 (249)

Synthesis of 4-Quinolone N-Oxides via Controlled Partial Hydrogenation of 2-Nitrobenzoyl Enamines

An operationally simple procedure for the synthesis of 2-alkyl-4-quinolone N-oxides, relying on controlled platinum-catalyzed partial hydrogenation of 2-nitrobenzoyl enamines, has been demonstrated. The P.
Francisco, Alonso, Plamen, Angelov, Paraskev, Nedialkov, Yordanka, Mollova-Sapundzhieva   +3 more
core   +1 more source

Ofloxacin plus Rifampicin versus Doxycycline plus Rifampicin in the treatment of brucellosis: a randomized clinical trial [ISRCTN11871179]

BMC Infectious Diseases, 2004
Background The combination therapies recommended by the World Health Organization for treatment of brucellosis are doxycycline plus rifampicin or doxycycline plus streptomycin. Although highly successful results have been obtained with these two regimens,
Kayas Derya, Sencan Irfan, Karabay Oguz, Şahin Idris   +3 more
doaj   +1 more source

4-Quinolone fused heterocyclic ring systems by intramolecular reactions of 4-quinolone-2-carboxamides [PDF]

, 2014
A versatile synthetic route to new 4-quinolone-based polycyclic systems is described. TFA-catalyzed intramolecular reaction of N-unsubstituted quinolone-2-carboxylic acid amides gives structurally diverse compounds, depending on the length of the chain ...
R. Cincinelli, S. Dallavalle, G. Beretta, L. Musso   +3 more
core   +1 more source

Treatment Choices for Acute Canine Otitis Externa in Sweden, Finland and Norway: A Comparative Study With a Focus on Antibiotic Use

Veterinary Dermatology, EarlyView.
Background: Canine otitis externa (COE) is one of the most frequently recorded disorders in veterinary practices, making it an important focus for antibiotic stewardship. Hypothesis/Objectives: To investigate and compare treatment regimens for acute COE in Finland, Norway and Sweden, with a focus on antibiotic use.
Kaisa Saarinen, Ditte Ljungquist, Riitta Seppänen, Mirja Kaimio, Anna‐Maria Andersson   +4 more
wiley   +1 more source

Implicación de diversos mecanismos de resistencia a quinolonas en bacilos Gram-negativos: Diseño de una nueva fluoroquinolona [PDF]

, 2008
[spa] DE LA TESIS: Desde la aparición de las quinolonas, las resistencias bacterianas a las mismas han evolucionado de forma paralela. Conforme han ido apareciendo nuevas moléculas con mayor capacidad bactericida y mejores parámetros farmacodinámicos ...
Sánchez Céspedes, Javier
core  

Aquatic Environments as Hotspots of Transferable Low-Level Quinolone Resistance and Their Potential Contribution to High-Level Quinolone Resistance

, 2022
The disposal of antibiotics in the aquatic environment favors the selection of bacteria exhibiting antibiotic resistance mechanisms. Quinolones are bactericidal antimicrobials extensively used in both human and animal medicine.
Christopher Concha, Concha, Christopher, Lee, Matthew R., Godoy, Félix A., Félix A. Godoy, Claudio D. Miranda, Matthew R. Lee, Miranda, Claudio D.   +7 more
core   +1 more source

Whole Genome Characterization of Klebsiella Strains in European Hedgehogs and Human Nosocomial Settings Identified Shared Sequence Types, Antimicrobial Resistance Genes and Plasmids

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Klebsiella pneumoniae is a pathogen associated with healthcare‐acquired infections and antimicrobial resistance (AMR) to beta‐lactams and carbapenems. Although wild animals are not typically exposed to antibiotics, they can harbour resistant strains. The European hedgehog (Erinaceus europaeus) is increasingly found in urban areas,
Biel Garcias, Chiara Seminati, Carolin M. Kobras, Samuel K. Sheppard, Rafael A. Molina‐López, Laila Darwich   +5 more
wiley   +1 more source

Quinolone resistance mechanisms among third-generation cephalosporin resistant isolates of Enterobacter spp. in a Bulgarian university hospital

, 2019
Rumyana Markovska,1 Temenuga Stoeva,2 Dobromira Dimitrova,2 Lyudmila Boyanova,1 Petya Stankova,1 Kalina Mihova,3 Ivan Mitov11Department of Medical Microbiology, Medical University of Sofia, Sofia, Bulgaria; 2Department of Microbiology, University ...
Stoeva T, Dimitrova D, Boyanova L, Stankova P, Mitov I, Markovska R, Mihova K   +6 more
core  

Occurrence of Antimicrobial Resistance in Kocuria rhizophila Bacteria Isolated From Salmo munzuricus (Teleostei: Salmonidae) Samples in Natural Resources

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
This study examined the antibiotic susceptibility of Kocuria rhizophila isolated from Salmo munzuricus samples taken from the Munzur River. The isolates are resistant to Penicillin G, moderately susceptible to gentamicin and tetracycline, and highly susceptible to amoxicillin and ampicillin.
Bülent KAR
wiley   +1 more source

One Health Insights From Pteropus medius: Nipah Virus Spillover, Microbiota, and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury, Shah Md Tanvir Khan, Sajal Roy, Md. Shohel Al Faruk   +3 more
wiley   +1 more source