Results 81 to 90 of about 71,327 (249)

Rare-Earth Metal Complexes of the Antibacterial Drug Oxolinic Acid: Synthesis, Characterization, DNA/Protein Binding and Cytotoxicity Studies

Molecules, 2020
“Drug repositioning” is a current trend which proved useful in the search for new applications for existing, failed, no longer in use or abandoned drugs, particularly when addressing issues such as bacterial or cancer cells resistance to current ...
Ana-Madalina Maciuca, Alexandra-Cristina Munteanu, Mirela Mihaila, Mihaela Badea, Rodica Olar, George Mihai Nitulescu, Cristian V. A. Munteanu, Marinela Bostan, Valentina Uivarosi   +8 more
doaj   +1 more source

Infectious bacterial keratitis management in a Swedish region: Risk factors, treatment and time‐to‐resolution

Acta Ophthalmologica, EarlyView.
Abstract Purpose To report treatment patterns, time‐to‐resolution (TTR) and aetiologies of bacterial keratitis (BK) infections treated in a specialized hospital‐based cornea clinic in Sweden. Methods Retrospective study based on electronic health records screened during the period 2010–2019. The study included only culture‐confirmed cases of BK.
Jenny Roth, Antonio Filipe Macedo, Sofia Somajo, Lukas Tannerfeldt, Baris Toprak, Neil Lagali   +5 more
wiley   +1 more source

Quinolone Analogue Inhibits Tubulin Polymerization and Induces Apoptosis Via Cdk1-Involved Signaling Pathways

, 2008
Cancer chemotherapeutic agents that interfere with tubulin/ microtubule function are in extensive use. Quinolone is a common structure in alkaloids and its related components exhibit several pharmacological activities.
陳依呈;潘秀玲;鄧哲明;郭盛助;林宗平;何藴芳;黃煜珺;顧記華, CHEN, YING-CHENG;PAN, SHIOW-LIN;TENG, CHE-MING;KUO, SHENG-CHU;LIN, TSUNG-PING;HO, YUNN-FANG;HUANG, YU-CHUN;GUH, JIH-HWA   +1 more
core  

Diels-Alder Reaction of N-Benzyl-3-nitro-2 (1H)-quinolone [PDF]

, 2004
Diels-Alder (DA) reaction of N-benzyl-3-nitro-2(1H)-quinolone with 1,3-butadiene gave the phenanthridone under the atmosphere, and afforded DA adducts under the high pressure condition.departmental bulletin ...
Fujita, Reiko, 若松, 秀章, 藤田, 礼子, フジタ, レイコ, ワカマツ, ヒデアキ, Wakamatsu, Hideaki, Wakayanagi, Sota, 若柳, 聡太, ワカヤナギ, ソウタ   +8 more
core  

Quinolone-Cation Interactions: A Review

, 1991
The quinolone class of antibiotics is enjoying a recent resurgence in interest and use due to the development of improved compounds. Norfloxacin, ciprofloxacin, and, most recently, ofloxacin have been marketed.
Edward A. Hartshorn, Ben M. Lomaestro, George R. Bailie   +2 more
core   +1 more source

2002–2022 Quinolone Resistance in Escherichia coli of Swine in Mainland China: A Meta-Analysis

Veterinary Sciences
Swine have emerged as significant reservoirs of antibiotic-resistant strains and genes. To establish a sound rationale for applying quinolone antibiotics in the swine industry, a meta-analysis was performed on the resistance rate of swine-derived ...
Xuelin Long, Shujun Liu, Runmin Kang, Yue Sun, Mingyue Tian, Lijun Zhao, Changwei Lei, Hongning Wang, Xin Yang   +8 more
doaj   +1 more source

Two new 2-alkylquinolones, inhibitory to the fish skin ulcer pathogen Tenacibaculum maritimum, produced by a rhizobacterium of the genus Burkholderia sp.

Beilstein Journal of Organic Chemistry, 2018
Exploration of rhizobacteria of the genus Burkholderia as an under-tapped resource of bioactive molecules resulted in the isolation of two new antimicrobial 2-alkyl-4-quinolones.
Dandan Li, Naoya Oku, Atsumi Hasada, Masafumi Shimizu, Yasuhiro Igarashi   +4 more
doaj   +1 more source

Patch Testing in Paediatric Drug Hypersensitivity Reactions: Current Evidence and Clinical Implications

Contact Dermatitis, EarlyView.
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti, Francesco Catamerò, Giulia Liccioli, Leonardo Tomei, Simona Barni, Mattia Giovannini, Lucrezia Sarti, Francesca Mori   +7 more
wiley   +1 more source

Adding gentamicin to fluoroquinolone-based antimicrobial prophylaxis reduces transrectal ultrasound-guided prostate biopsy-related infection rate

Urological Science, 2016
Objective: Transrectal ultrasound-guided prostate (TRUS) biopsy is the standard method for the diagnosis of prostate cancer. Quinolone-based prophylaxis before a TRUS biopsy of the prostate is the most common regimen worldwide.
Tzuo-Yi Hsieh, Yu-Lin Kao, Shao-Chuan Wang, Wen-Jung Chen, Sung-Lang Chen   +4 more
doaj   +1 more source

Serotypic and Genomic Diversity of Vibrio anguillarum in Rainbow Trout Farms in Turkey: Implications for Vibriosis Control and Vaccine Candidate Selection

Journal of Fish Diseases, EarlyView.
ABSTRACT Outbreaks of vibriosis caused by Vibrio anguillarum are a persistent constraint on rainbow trout (Oncorhynchus mykiss) aquaculture. However, information on the population structure of field strains in Turkey has been lacking. Here, we report the first systematic serotypic, proteomic, and genomic characterization of 23 V.
Soner Altun, Muhammed Duman, Jesús L. Romalde, Nihed Ajmi, Gorkem Tasci, Cuneyt Ozakin, Nazmiye Ulku Tuzemen, Bekir Akça, Sebahattin Ergün, Sevdan Yılmaz, Izzet Burcin Saticioglu   +10 more
wiley   +1 more source