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The Research Status, Potential Hazards and Toxicological Mechanisms of Fluoroquinolone Antibiotics in the Environment

open access: yesAntibiotics, 2023
Fluoroquinolone antibiotics are widely used in human and veterinary medicine and are ubiquitous in the environment worldwide. This paper recapitulates the occurrence, fate, and ecotoxicity of fluoroquinolone antibiotics in various environmental media ...
Jia Du, Ying Pan, Junhong Tang
exaly   +3 more sources

Risk assessment and transmission of fluoroquinolone resistance in drug-resistant pulmonary tuberculosis: a retrospective genomic epidemiology study

open access: yesScientific Reports
Fluoroquinolone resistance is a major challenge in treating Multidrug-Resistant Tuberculosis globally. The GenoType MTBDRsl Ver 2.0, endorsed by the WHO, was used to characterize fluoroquinolone resistance. The fluoroquinolone resistance rates in the MDR-
Usharani Brammacharry   +1 more
exaly   +2 more sources

Shifting hierarchy of the conjunctival florae in the patients employed a long-time topical fluoroquinolone [PDF]

open access: yesInternational Journal of Ophthalmology, 2020
AIM: To observe the shifting hierarchy of the conjunctival florae in the patients who employed a long-time topical fluoroquinolone and characterize the consequent variations of their antibiotic sensitivity and virulence.
Xue-Hui Zhang   +3 more
doaj   +1 more source

Regeneration difficulties in patients with FQAD can limit the use of iPSc-based cell therapy

open access: yesStem Cell Research & Therapy, 2022
Etiopathogenesis of fluoroquinolone-associated disability (FQAD) syndrome is not fully understood, yet research could progress by utilizing induced pluripotent stem cells (iPSc) from people with this syndrome. Similarly, iPSc, or rather their derivatives,
Dagmara Grot   +5 more
doaj   +1 more source

Fosfomycin for Antibiotic Prophylaxis in Men Undergoing a Transrectal Prostate Biopsy: A Systematic Review and Meta-Analysis

open access: yesMedicina, 2023
Background and Objectives: To assess the effects of fosfomycin compared with other antibiotics as a prophylaxis for urinary tract infections (UTIs) in men undergoing transrectal prostate biopsies. Materials and Methods: We searched multiple databases and
Hui Mo Gu   +10 more
doaj   +1 more source

Cardiotoxicity of fluoroquinolones [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2002
Currently marketed fluoroquinolones enjoy an admirable safety profile that is not matched by any other antibiotic group. The widespread use of fluoroquinolones in the elderly, who are susceptible to cardiac arrhythmias because of underlying heart diseases, metabolic derangement and use of anti-arrhythmic agents and other medications that prolong the QT
Ethan, Rubinstein, John, Camm
openaire   +2 more sources

Overexpression of Salmonella enterica serovar Typhi recA gene confers fluoroquinolone resistance in Escherichia coli DH5α [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2015
A spontaneous fluoroquinolone-resistant mutant (STM1) was isolated from its parent Salmonella enterica serovar Typhi (S. Typhi) clinical isolate. Unlike its parent isolate, this mutant has selective resistance to fluoroquinolones without any change in ...
M.A.M. Yassien, M.A. Elfaky
doaj   +3 more sources

Positive Association Between Fluoroquinolone Exposure and Tendon Disorders: A Nationwide Population-Based Cohort Study in Taiwan

open access: yesFrontiers in Pharmacology, 2022
Introduction: Fluoroquinolone exposure is reportedly associated with a higher risk of tendon disorders, tendonitis, or tendon rupture. However, studies in East Asian populations have not confirmed these risks in patients with comorbidities or concomitant
Chun-Kai Chang   +16 more
doaj   +1 more source

Trend of multidrug and fluoroquinolone resistance in Mycobacterium tuberculosis isolates from 2010 to 2014 in Korea: a multicenter study [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2019
Background/Aims This study was conducted to evaluate the recent prevalence and trend of anti-tuberculosis (TB) drug resistance with a focus on multidrug-resistance (MDR) and fluoroquinolone resistance in South Korea.
Hyeonseok Kim   +7 more
doaj   +1 more source

Safety of fluoroquinolones

open access: yesRevista Española de Quimioterapia, 2023
Fluoroquinolones (FQs) are one of the most commonly prescribed classes of antibiotics. Although they were initially well tolerated in randomized clinical trials, subsequent epidemiological studies have reported an increased risk of threatening, severe, long-lasting, disabling and irreversible adverse effects (AEs), related to neurotoxicity and collagen
José Barberán   +6 more
openaire   +2 more sources

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