Results 121 to 130 of about 75,013 (302)
Andrology, EarlyView.Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre +5 more
wiley +1 more source
Selection of multiple antibiotic resistance by quinolones, beta-lactams, and aminoglycosides with special reference to cross-resistance between unrelated drug classes [PDF]
, 1984 Christine C. Sanders +3 more
openalex +1 more source
Protein tyrosine phosphatases as emerging targets for cancer immunotherapy
British Journal of Pharmacology, EarlyView.Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley +1 more source
Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential
British Journal of Pharmacology, EarlyView.Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley +1 more source
Comparative in vitro activity of PD 127,391, a new fluorinated 4-quinolone derivative [PDF]
, 1988 S. Ragnar Norrby +1 more
openalex +1 more source
Clinical &Experimental Allergy, EarlyView.Beta‐lactam antibacterials, including penicillins and other beta‐lactam antibacterials showed the highest signal strength and reporting frequency. These findings underscore the importance of evaluating the long‐term outcomes of antibiotic‐induced anaphylaxis to improve prevention and management strategies. ABSTRACT Background Despite antibiotic‐induced
Jaehyeong Cho +13 more
wiley +1 more source
Skin graft bolstered by negative pressure therapy in chronic wounds: A systematic review
Journal of the European Academy of Dermatology and Venereology, EarlyView.NPWT improve the graft take rate of skin graft in chronic ulcer, with an excellent safety and tolerance profile. We have identified various subgroups in which NPWT appears to be more effective, such as venous ulcers, men, patients aged under 65, without arterial disease and those with prior antibiotic therapy.
M. Gamel, M. Gael, A. C. Bursztejn
wiley +1 more source
Characterization of mechanisms of quinolone resistance in Pseudomonas aeruginosa strains isolated in vitro and in vivo during experimental endocarditis [PDF]
, 1989 Suzanne Chamberland +4 more
openalex +1 more source
Journal of Internal Medicine, EarlyView.Abstract Objectives To assess the association between infections, assessed by antibiotic reimbursement, and the occurrence of giant cell arteritis (GCA) and/or polymyalgia rheumatica (PMR). Methods We conducted a nested case–control study from the French cohort E3N‐European Prospective Investigation into Cancer and Nutrition, which has followed 98,995 ...
Lucas Pacoureau +6 more
wiley +1 more source