Results 111 to 120 of about 71,327 (249)
Anti-Helicobacter pylori Activity of Quinolone Alkaloids from Evodiae Fructus.
A biologically monitored fractionation of methanol extract of the fruit of Evodia rutaecarpa led to the isolation of six quinolone alkaloids, evocarpine (1), 1-methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone (2), 1-methyl-2-[(6Z,9Z)-6,9 ...
Eun Ah Bae +8 more
core +1 more source
How Host Phylogeny, Diet, and Habitat Affect Gut Microbial Diversity in Wild Snakes
Gut microbiota plays critical roles in host digestion, immune regulation, neurochemical signaling, and metabolic homeostasis. Based on wild snakes (73 individuals from 23 species) from China, we explored the composition, characteristics, and functions of gut microbes across different groups using fecal metagenomic samples; further we explored the ...
Jiaqi Zhang +7 more
wiley +1 more source
Advances in immunoassay methods for quinolones
Quinolones (QNs) are highly favored for their broad-spectrum antibacterial effects. However, the overuse of QNs in animal feed can lead to their residues entering the food chain, thus posing potential hazards to the environment and human health.
WU Mengjiao +5 more
doaj +1 more source
Trends in Enterobacteriaceae Resistance Patterns: A Nine‐Year Retrospective Study From North Lebanon
ABSTRACT Background and Aims Antimicrobial resistance (AMR) in Enterobacteriaceae poses a critical threat to global health, particularly in regions where antibiotic misuse and limited surveillance prevail. Intensive care units (ICUs) act as focal points for resistance emergence and dissemination. This study aimed to evaluate long‐term resistance trends
Mazen Zaylaa +12 more
wiley +1 more source
2-Alkyl-4-quinolone interactions with PqsR.
(A) Structures of 2-heptyl-3-hydroxy-4(1H)-quinolone (PQS), 2-heptyl-4(1H)-quinolone (2-heptyl-4-hydroxyquinoline, HHQ) and 2-nonyl-4(1H)-quinolone (2-nonyl-4-hydroxyquinoline, NHQ); (B) A stereo diagram of the topology of the PqsRCBD-NHQ complex showing
Christian Pustelny (437508) +10 more
core +1 more source
Quinolone-resistant Campylobacter jejuni have been increasing worldwide. Quinolones exert their antibacterial activity by inhibiting DNA gyrase, but most of the isolates acquire quinolone resistance via an amino acid substitution in the A subunit of DNA ...
Kentaro Koide +10 more
doaj +1 more source
The graphical abstract outlines that samples from milk, faeces and soil were tested for Enterococcus avium using culture, PCR and genome sequencing.2. Overall, prevalence of E. avium was 56.3%, and 93.5% of isolates were multidrug‐resistant.3. Genomic analysis revealed six ARGs, 43–45 VFGs and 4–6 bacteriocins.4.
Monira Rahaman +10 more
wiley +1 more source
Multidrug‐resistant Salmonella was detected in 13.5% of the raw meat samples in Chattogram, with resistance to multiple antibiotics and a high prevalence of the blaTEM gene. These findings highlight significant foodborne AMR risks and underscore the need for urgent One Health interventions to protect public health.
Mukta Das Gupta +7 more
wiley +1 more source
Quinolone-1-(2H)-ones as hedgehog signalling pathway inhibitors
A series of quinolone-2-(1H)-ones derived from the Ugi-Knoevenagel three- and four-component reaction were prepared exhibiting low micromolar cytotoxicity against a panel of eight human cancer cell lines known to possess the Hedgehog Signalling Pathway ...
Trieu N. Trinh (4270303) +8 more
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