Results 131 to 140 of about 103,486 (339)

Anti Microbial Resistance Profile of E. coli isolates From Tropical Free Range Chickens [PDF]

, 2005
Normal intestinal flora of humans and animals constitute enormous reservoir of resistance genes for potentially pathogenic bacteria and may serve as major indictors of selection pressure exerted by anti-microbial use in a given population.
A BI, Udedibie, K F, Chah, Okoli I, Charles, P TE, Ozoh   +3 more
core   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones [PDF]

, 2016
Our previous paper (Wilkinson et al, 2016) used high-resolution cryo-electron microscopy to solve the structure of the Escherichia coli RecBCD complex, which acts in both the repair of double-stranded DNA breaks and the degradation of bacteriophage DNA ...
Aedo, Afonine, Amundsen, Amundsen, Bannister, Baños-Sanz, Cano, Cirz, CLSI, Cole, Court, Court, Cronan, Darrigo, Datta, Dillingham, Emsley, Forage, González-Soltero, Henderson, Kennaway, Kulkarni, Li, Liu, Liu, López, McDaniel, Murphy, Murphy, Murphy, Muyrers, Paczosa, Pettersen, Robinson, Sakaki, Scheres, Singleton, Tamae, Urnavicius, Wang, Wiegand, Wigley, Wilkinson, Zhang, Zhang   +44 more
core   +4 more sources

Fluorescent Antibiotics: Bridging Diagnostic and Therapy in the Fight against Bacterial Infections

Small Science, EarlyView.
This review critically evaluates fluorescent antibiotics as promising agents combining diagnostic precision with therapeutic efficacy. It highlights advances in probe design, chemical conjugation strategies, real‐time imaging applications, selective pathogen detection, and targeted therapy. The potential to combat antimicrobial resistance is discussed,
Tan Phuoc Ton, Richard Bright, Vi Khanh Truong, Krasimir Vasilev   +3 more
wiley   +1 more source

Could traces of fluoroquinolones in food induce ciprofloxacin resistance in Escherichia coli and Klebsiella pneumoniae? An in vivo study in Galleria mellonella with important implications for maximum residue limits in food

Microbiology Spectrum
We hypothesized that the residual concentrations of fluoroquinolones allowed in food (acceptable daily intake—ADIs) could select for ciprofloxacin resistance in our resident microbiota.
Zina Gestels, Yuliia Baranchyk, Dorien Van den Bossche, Jolein Laumen, Said Abdellati, Basil Britto Xavier, Sheeba Santhini Manoharan-Basil, Chris Kenyon   +7 more
doaj   +1 more source

Contrasting effects of fluoroquinolone antibiotics on the expression of the collagenases, matrix metalloproteinases (MMP)-1 and -13, in human tendon-derived cells [PDF]

, 2005
Fluoroquinolone antibiotics may cause tendon pain and rupture. We reported previously that the fluoroquinolone ciprofloxacin potentiated interleukin (IL)-1ß-stimulated expression of matrix metalloproteinases (MMP)-3 and MMP-1 in human tendon-derived ...
Corps, A.N, Curry, V.A, Harrall, R.L, Hazleman, B.L, Riley, Graham   +4 more
core   +1 more source

Analysis and Study of Covalent Organic Frameworks in Electrochemical Sensors for Water Environment Pollutant Detection

Small Structures, EarlyView.
This summary highlights covalent organic framework (COF)‐based electrochemical sensors for detecting water pollutants like antibiotics, heavy metals, pesticides, bisphenols, and toxins. It covers diverse COF synthesis methods, including solvothermal, ionothermal, and microwave‐assisted techniques.
Bo Long, Qi Liu, Qian Zhang, Qiongqiong Xing, Liying Deng, Fangfang Qu, Liwei Wang, Dapeng Ye, Zhanhui Yuan   +8 more
wiley   +1 more source

DNA Gyrase Is the Target for the Quinolone Drug Ciprofloxacin in Arabidopsis thaliana*

Journal of Biological Chemistry, 2015
The Arabidopsis thaliana genome contains four genes that were originally annotated as potentially encoding DNA gyrase: ATGYRA, ATGYRB1, ATGYRB2, and ATGYRB3.
Katherine M. Evans-Roberts, L. Mitchenall, M. K. Wall, J. Leroux, J. Mylne, A. Maxwell   +5 more
semanticscholar   +1 more source

Bifidobacterium bifidum G9‐1 Survives in the Intestinal Environment and Influences the Gut Microbiota Despite the Presence of Antimicrobials

Microbiology and Immunology, EarlyView.
ABSTRACT Probiotics can help prevent antibiotic‐associated diarrhea; however, those lacking antimicrobial resistance may be ineffective during antimicrobial treatment. Here, we aimed to examine the effects of antimicrobials on the probiotic strain Bifidobacterium bifidum G9‐1 (BBG9‐1).
Haruka Yokota, Yutaka Makizaki, Yoshiki Tanaka, Hiroshi Ohno   +3 more
wiley   +1 more source

Adding gentamicin to fluoroquinolone-based antimicrobial prophylaxis reduces transrectal ultrasound-guided prostate biopsy-related infection rate

Urological Science, 2016
Objective: Transrectal ultrasound-guided prostate (TRUS) biopsy is the standard method for the diagnosis of prostate cancer. Quinolone-based prophylaxis before a TRUS biopsy of the prostate is the most common regimen worldwide.
Tzuo-Yi Hsieh, Yu-Lin Kao, Shao-Chuan Wang, Wen-Jung Chen, Sung-Lang Chen   +4 more
doaj   +1 more source