Results 131 to 140 of about 136,091 (317)

Chemical structure and pharmacokinetics of novel quinolone agents represented by avarofloxacin, delafloxacin, finafloxacin, zabofloxacin and nemonoxacin

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2016
Quinolones are potent antimicrobial agents with a basic chemical structure of bicyclic ring. Fluorine atom at position C-6 and various substitutions on the basic quinolone structure yielded fluoroquinolones, namely norfloxacin, ciprofloxacin ...
B. Kocsis, J. Domokos, D. Szabo
semanticscholar   +1 more source

Germicidal potential and skin compatibility of an innovative UVC phototherapy device emitting at 234 nm

open access: yesPhotochemistry and Photobiology, EarlyView.
A phototherapy device emitting principally at 234 nm was assessed for antimicrobial efficacy against Methicillin‐resistant Staphylococcus aureus and evaluated for skin health hazards. Abstract Chronic wounds are a major healthcare issue affecting more than 10 million Americans each year, with a 5‐year survival similar to cancer and costing the ...
Zheng Tang   +4 more
wiley   +1 more source

Changes in the Dispensing of Antibiotics to Australian Children Between 2013 and 2023: Are We Heading in the Right Direction?

open access: yesPaediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Antimicrobial resistance (AMR) poses a critical public health issue, exacerbated by the overuse and misuse of antibiotics. Children are particularly susceptible to bacterial infections and are frequently prescribed antibiotics. Objective This study examined trends in antibiotic dispensing to children aged under 13 years in Australia
Erin Kelty   +8 more
wiley   +1 more source

NEW QUINOLONE-BASED COMPOUNDS: SYNTHESIS, CRYSTAL STRUCTURES AND BIOLOGICAL ACTIVITIES

open access: yesScientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2019
A new quinoline-based compounds have been synthesized from 2-oxo-1,2-dihydroquinoline-4-carboxylic acid (2) and involved in alkylation reactions using phase transfer catalysis conditions.
YASSIR FILALI BABA   +5 more
doaj  

A “Double-Edged” Scaffold: Antitumor Power within the 
Antibacterial Quinolone

open access: yesCurrent Medicinal Chemistry, 2016
In the late 1980s, reports emerged describing experimental antibacterial quinolones having significant potency against eukaryotic Type II topoisomerases (topo II) and showing cytotoxic activity against tumor cell lines.
G. Bisacchi, Michael R. Hale
semanticscholar   +1 more source

A retrospective study of the efficacy and safety of levofloxacin in children with severe infection

open access: yesFrontiers in Pediatrics
ObjectivesLevofloxacin is widely used because of its broad-spectrum antimicrobial activity and convenient dosing schedule. However, the relevance of its use in children remains to be investigated.
Zhang Junqi   +6 more
doaj   +1 more source

Ruthenium Complexes in Protein Science: Heading a New Generation of Therapeutic and Analytical Tools

open access: yesAngewandte Chemie, Volume 138, Issue 4, 22 January 2026.
This review presents the latest advances in the development of ruthenium complexes within the field of protein science, highlighting their potential applications in biomedical and bioanalytical fields. Abstract Ruthenium complexes are distinguished by their versatile coordination chemistry, redox behaviors and photochemical properties. In recent years,
Liyan Zhang, Yun Chen, Sylvestre Bonnet
wiley   +2 more sources

Diagnosis and treatment of gastric abscess by endoscopic ultrasound: A mini‐review of the preliminary application

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
Abstract Gastric abscess is a rare condition caused by gastric barrier damage. It is easily misdiagnosed in clinical practice as a cancer recurrence or submucosal tumor, especially after surgery or endoscopic submucosal dissection. With a relatively high mortality rate, the cause and clinical characteristics of gastric abscesses are obscure.
Jia Xie, Mo‐Jin Wang, Rui Wang
wiley   +1 more source

Advances in immunoassay methods for quinolones

open access: yesShipin yu jixie
Quinolones (QNs) are highly favored for their broad-spectrum antibacterial effects. However, the overuse of QNs in animal feed can lead to their residues entering the food chain, thus posing potential hazards to the environment and human health.
WU Mengjiao   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy