Results 181 to 190 of about 103,486 (339)
Light‐Activated Pharmacological Tools for Exploring the Cholinergic System
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni+5 more
wiley +1 more source
Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota
Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog+8 more
wiley +2 more sources
Isolation and Structure Elucidation of Three Quinolone Alkaloids fromEvodia rutaecarpa
Toshiya Kamikado+4 more
openalex +1 more source
A point mutation in IAA34 confers resistance to the auxin herbicide 2,4‐D in Sisymbrium orientale
A point mutation in domain IV of SoAux/IAA34‐R provides resistance to 2,4‐D. Abstract BACKGROUND Sisymbrium orientale has evolved resistance to 2,4‐D in Australia due to a 27 bp deletion in SoIAA2. However, one population of Sisymbrium orientale resistant to 2,4‐D (R1) did not contain the SoIAA2Δ27, suggesting another 2,4‐D resistance mechanism was ...
Yuanlin Qi+3 more
wiley +1 more source
This review explores the potential of antimicrobial peptides (AMPs) and nanotechnology for the treatment of gastrointestinal infections. It analyzes bacterial resistance mechanisms, the antimicrobial actions of AMPs, and advances in nanocarriers, such as lipid‐based, polymeric, metallic, and mesoporous silica systems, that enhance peptide protection ...
Christian Shleider Carnero Canales+10 more
wiley +1 more source
Comparative in vitro activity of PD 127,391, a new fluorinated 4-quinolone derivative [PDF]
S. Ragnar Norrby+1 more
openalex +1 more source
• The prevalence of ESBL‐E. coli in cats and dogs in central Peninsular Malaysia was 10.6%. • Dogs are at a greater risk of carrying the bacteria, and among pets sharing feeding area and pets with a history of gastrointestinal symptoms. • Co‐resistance to more than three types of tested antibiotics for the ESBL‐E.
Khaleeda Azalea Dzulkifli+4 more
wiley +1 more source
Limonoids and quinolone alkaloids from Evodia rutaecarpa Bentham.
Tohru Sugimoto+3 more
openalex +2 more sources