Results 11 to 20 of about 44,560 (245)
Pharmacy, 2019 Quinolones are the second most common antibiotic class associated with drug-induced allergic reactions, but data on quinolone allergy are scarce. This review article discusses the available evidence on quinolone allergy, including prevalence, risk ...
Edoabasi U. McGee +5 more
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Molecules, 2020 In order to seek novel technetium-99m bacterial infection imaging agents, a ciprofloxacin xanthate (CPF2XT) was synthesized and radiolabeled with [99mTcN]2+ core to obtain the 99mTcN-CPF2XT complex, which exhibited high radiochemical purity ...
Si’an Fang +5 more
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Frontiers in Pharmacology, 2020 BackgroundThe use of quinolones has been associated with the development of serious and persistent adverse drug reaction (ADR) mainly affecting muscles, joints and the nervous system.
Cristina Scavone +12 more
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The Current Case of Quinolones: Synthetic Approaches and Antibacterial Activity
Molecules, 2016 Quinolones are broad-spectrum synthetic antibacterial drugs first obtained during the synthesis of chloroquine. Nalidixic acid, the prototype of quinolones, first became available for clinical consumption in 1962 and was used mainly for urinary tract ...
Abdul Naeem +4 more
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Metal Complexes of Quinolone Antibiotics and Their Applications: An Update
Molecules, 2013 Quinolones are synthetic broad-spectrum antibiotics with good oral absorption and excellent bioavailability. Due to the chemical functions found on their nucleus (a carboxylic acid function at the 3-position, and in most cases a basic piperazinyl ring ...
Valentina Uivarosi
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Pharmaceuticals, 2022 The rise in multiple-drug-resistant (MDR) phenotypes in Gram-negative pathogens is a major public health crisis. Pseudomonas aeruginosa is one of the leading causes of nosocomial infections in clinics. Treatment options for P.
Ashish Kothari +8 more
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Nontargeted Metabolomics Reveals the Multilevel Response to Antibiotic Perturbations
Cell Reports, 2017 Microbes have shown a remarkable ability in evading the killing actions of antimicrobial agents, such that treatment of bacterial infections represents once more an urgent global challenge.
Mattia Zampieri +3 more
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Increasing Antimicrobial Resistance and Narrowing Therapeutics in Typhoidal Salmonellae [PDF]
Journal of Clinical and Diagnostic Research, 2013 Multidrug-resistant typhoid fever (MDRTF) is a major public health problem in developing countries and is an emerging problem in the developed world.
Jaspal Kaur
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Antibiotics in Raw Meat Samples: Estimation of Dietary Exposure and Risk Assessment
Toxics, 2022 The extensive use of antibiotics in livestock farming poses increased concerns for human health as residues of these substances are present in edible tissues.
Athina Stavroulaki +11 more
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