Results 11 to 20 of about 33,933 (196)
Pharmaceuticals, 2022 The rise in multiple-drug-resistant (MDR) phenotypes in Gram-negative pathogens is a major public health crisis. Pseudomonas aeruginosa is one of the leading causes of nosocomial infections in clinics. Treatment options for P.
Ashish Kothari +8 more
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Frontiers in Pharmacology, 2022 The emergence of Plasmodium falciparum (Pf) parasite strains tolerant of the artemisinin component and resistant to the other drug component in artemisinin combination therapies (ACTs) used for treatment now markedly complicates malaria control.
Daniel J. Watson +5 more
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The Current Case of Quinolones: Synthetic Approaches and Antibacterial Activity
Molecules, 2016 Quinolones are broad-spectrum synthetic antibacterial drugs first obtained during the synthesis of chloroquine. Nalidixic acid, the prototype of quinolones, first became available for clinical consumption in 1962 and was used mainly for urinary tract ...
Abdul Naeem +4 more
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Zhongguo shipin weisheng zazhi, 2022 ObjectiveTo study the matrix effects （MEs） and the compensation measures of 15 quinolones （QNs） determination in animal derived food by high performance liquid chromatography-tandem mass spectrometry （HPLC-MS/MS） .MethodsFish， pork and chicken as typical
LI Daoxia +5 more
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Metal Complexes of Quinolone Antibiotics and Their Applications: An Update
Molecules, 2013 Quinolones are synthetic broad-spectrum antibiotics with good oral absorption and excellent bioavailability. Due to the chemical functions found on their nucleus (a carboxylic acid function at the 3-position, and in most cases a basic piperazinyl ring ...
Valentina Uivarosi
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Proceedings, 2020 Quinolones are effective against a broad range of bacterial species and provide potent treatmentoptions for a few infections [1,2]. [...]
Lucia Pintilie +3 more
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Increasing Antimicrobial Resistance and Narrowing Therapeutics in Typhoidal Salmonellae [PDF]
Journal of Clinical and Diagnostic Research, 2013 Multidrug-resistant typhoid fever (MDRTF) is a major public health problem in developing countries and is an emerging problem in the developed world.
Jaspal Kaur
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Frontiers in Microbiology, 2022 Recent studies have shown that not only resistance, but also tolerance/persistence levels can evolve rapidly in bacteria exposed to repeated antibiotic treatments.
Aurore Perault +5 more
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Frequency Assay of qnr Genes in Enterobacteriaceae Isolated from Hospital and Urban Wastewaters in Karaj City [PDF]
آب و فاضلاب, 2021 In recent years, because of excessive and unregulated use of antibiotics, the threat of acquisition of antibiotic resistance by pathogens is growing. Hospitals are hotspots for antimicrobial-resistant bacteria (ARB) and will be ejected from hospitals via
Shirin Rezakhani +2 more
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Photochemical Cyclization of Tertiary Buta‐2,3‐dienamides to β‐Lactams Upon Triplet Energy Transfer
Angewandte Chemie, EarlyView.Energy transfer is the key to the successful photocyclization of the title compounds to 3,4‐disubstituted 2‐azetidinones. If the substituent at the nitrogen atom is primary (R2 = H), trans products are formed exclusively. The triplet state of xanthen‐9‐one (XT) was found to be quenched by an allene amide (R, R2 = H, R1 = Bn, and R3 = Ph) with a ...
Johannes Hofer +3 more
wiley +2 more sources