Frontiers in Microbiology, 2022 Recent studies have shown that not only resistance, but also tolerance/persistence levels can evolve rapidly in bacteria exposed to repeated antibiotic treatments.
Aurore Perault +5 more
doaj +1 more source
Frequency Assay of qnr Genes in Enterobacteriaceae Isolated from Hospital and Urban Wastewaters in Karaj City [PDF]
آب و فاضلاب, 2021 In recent years, because of excessive and unregulated use of antibiotics, the threat of acquisition of antibiotic resistance by pathogens is growing. Hospitals are hotspots for antimicrobial-resistant bacteria (ARB) and will be ejected from hospitals via
Shirin Rezakhani +2 more
doaj +1 more source
Targeting the hard to reach: Challenges and novel strategies in the treatment of intracellular bacterial infections: Targeting intracellular bacteria [PDF]
, 2016 Infectious diseases continue to threaten human and animal health and welfare globally, impacting millions of lives and causing substantial economic loss. The use of antibacterials has been only partially successful in reducing disease impact.
Good, L, Kamaruzzaman, N F, Kendall, S L
core +1 more source
Periodontology 2000, EarlyView., 2023 Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis +5 more
wiley +1 more source
Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients. [PDF]
, 2012 Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used ...
Alfredo Ponce-de-Leon +72 more
core +9 more sources
Periodontology 2000, EarlyView., 2023 Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera +4 more
wiley +1 more source
Prevalence and Antibiotic Susceptibility Patterns of Mycoplasma Hominis and Ureaplasma Urealyticum in Females with Genital Infections from Central Kerala, India [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Genital mycoplasmas namely Mycoplasma Hominis and Ureaplasma Urealyticum are sexually transmitted disease pathogens which are associated with genital infections, infertility, obstetric and neonatal complications.
SNEHA RAJAN, Suryakala R Nair
doaj +1 more source
Approaching zero : temporal effects of a restrictive antibiotic policy on hospital-acquired Clostridium difficile, extended-spectrum β-lactamase-producing coliforms and meticillin-resistant Staphylococcus aureus [PDF]
, 2013 A restrictive antibiotic policy banning routine use of ceftriaxone and ciprofloxacin was implemented in a 450-bed district general hospital following an educational campaign.
Christison, F. +5 more
core +3 more sources
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
Nontargeted Metabolomics Reveals the Multilevel Response to Antibiotic Perturbations
Cell Reports, 2017 Microbes have shown a remarkable ability in evading the killing actions of antimicrobial agents, such that treatment of bacterial infections represents once more an urgent global challenge.
Mattia Zampieri +3 more
doaj +1 more source