Results 11 to 20 of about 64,524 (236)

Antibiotics in Raw Meat Samples: Estimation of Dietary Exposure and Risk Assessment

open access: yesToxics, 2022
The extensive use of antibiotics in livestock farming poses increased concerns for human health as residues of these substances are present in edible tissues.
Athina Stavroulaki   +11 more
doaj   +1 more source

Potential Synergistic Antibiotic Combinations against Fluoroquinolone-Resistant Pseudomonas aeruginosa

open access: yesPharmaceuticals, 2022
The rise in multiple-drug-resistant (MDR) phenotypes in Gram-negative pathogens is a major public health crisis. Pseudomonas aeruginosa is one of the leading causes of nosocomial infections in clinics. Treatment options for P.
Ashish Kothari   +8 more
doaj   +1 more source

The evaluation of ADME and pharmacokinetic properties of decoquinate derivatives for the treatment of malaria

open access: yesFrontiers in Pharmacology, 2022
The emergence of Plasmodium falciparum (Pf) parasite strains tolerant of the artemisinin component and resistant to the other drug component in artemisinin combination therapies (ACTs) used for treatment now markedly complicates malaria control.
Daniel J. Watson   +5 more
doaj   +1 more source

Quinolones modulate ghrelin receptor signaling: potential for a novel small molecule scaffold in the treatment of cachexia [PDF]

open access: yes, 2018
Cachexia is a metabolic wasting disorder characterized by progressive weight loss, muscle atrophy, fatigue, weakness, and appetite loss. Cachexia is associated with almost all major chronic illnesses including cancer, heart failure, obstructive ...
Cano, Rafael   +8 more
core   +3 more sources

Matrix effects and compensation measures of quinolones detection in animal derived food by HPLC-MS/MS

open access: yesZhongguo shipin weisheng zazhi, 2022
ObjectiveTo study the matrix effects (MEs) and the compensation measures of 15 quinolones (QNs) determination in animal derived food by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) .MethodsFish, pork and chicken as typical
LI Daoxia   +5 more
doaj   +1 more source

Assessment of the genotoxicity of quinolone and fluoroquinolones contaminated soil with the Vicia faba micronucleus test [PDF]

open access: yes, 2012
The genotoxicity of quinolone and fluroquinolones was assessed using the micronucleus (MN) test on Viciafaba roots by direct contact exposure to a solid matrix.
Bousquet-Mélou, Alain   +7 more
core   +3 more sources

Synthesis and “In Silico” Evaluation of the Biological Activity of the New Dual Inhibitors of Gyrase DNA and Topoisomerase IV

open access: yesProceedings, 2020
Quinolones are effective against a broad range of bacterial species and provide potent treatmentoptions for a few infections [1,2]. [...] 
Lucia Pintilie   +3 more
doaj   +1 more source

Increasing Antimicrobial Resistance and Narrowing Therapeutics in Typhoidal Salmonellae [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
Multidrug-resistant typhoid fever (MDRTF) is a major public health problem in developing countries and is an emerging problem in the developed world.
Jaspal Kaur
doaj   +1 more source

Antimicrobial susceptibility of Neisseria gonorrheae strains in three regions of Armenia [PDF]

open access: yes, 2007
OBJECTIVE: There are no data available on gonococcal susceptibility in the Caucasus region. We aimed to determine in vitro antimicrobial susceptibility of Neisseria gonorrheae in Armenia in order to update the national treatment protocol.
Borisenko   +6 more
core   +2 more sources

SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]

open access: yes, 2018
Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania   +19 more
core   +1 more source

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