Results 31 to 40 of about 34,906 (202)
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
Nontargeted Metabolomics Reveals the Multilevel Response to Antibiotic Perturbations
Cell Reports, 2017 Microbes have shown a remarkable ability in evading the killing actions of antimicrobial agents, such that treatment of bacterial infections represents once more an urgent global challenge.
Mattia Zampieri +3 more
doaj +1 more source
Frontiers in Pharmacology, 2020 BackgroundThe use of quinolones has been associated with the development of serious and persistent adverse drug reaction (ADR) mainly affecting muscles, joints and the nervous system.
Cristina Scavone +12 more
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Microbiology Spectrum, 2023 Collateral sensitivity (CS) is an evolutionary trade-off by which acquisition of resistance to an antibiotic leads to increased susceptibility to another.
Sara Hernando-Amado +5 more
doaj +1 more source
Applied Sciences, 2021 Cisplatin is one of the most effective anticancer agents used to treat colon cancer, which is the third malignancy between the most common human cancers in the world, but the resistance developed represents an obstacle against the full success of ...
Mirela Mihaila +6 more
doaj +1 more source
Analytical methods for the determination of some selected 4-quinolone antibacterials
Reviews in Analytical Chemistry, 2017 A comprehensive review with 337 references for the analysis of some selected 4-quinolone drugs belonging to the first and second generations since 2006 up till now is presented. This group includes nalidixic acid, oxolinic acid, piromidic acid, pipemidic
Belal Fathallah +2 more
doaj +1 more source
Development of the quinolones [PDF]
Journal of Antimicrobial Chemotherapy, 2003 Since their discovery in the early 1960s, the quinolone group of antibacterials has generated considerable clinical and scientific interest. Nalidixic acid, the first quinolone to be developed, was obtained as an impurity during the manufacture of quinine.
Monique I, Andersson +1 more
openaire +2 more sources
Docking studies on novel analogs of quinolones against DNA gyrase of Escherichia coli [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2018 Context: Bacterial resistance to antibiotics is the inevitable consequence of the use of antimicrobial agents. Thus, quinolones are an important class of antibacterials; these agents generally consist of a 1-subtituted-1,4-dihydro-4-oxopyridine-3 ...
Cristian Davila +3 more
doaj
Infection and Drug Resistance, 2022 Mohamed F El-Badawy,1,* Emad M Eed,2,* Asmaa S Sleem,3 Azza AK El-Sheikh,4 Ibrahim A Maghrabi,5 Sayed F Abdelwahab6 1Department of Microbiology and Immunology, Faculty of Pharmacy, University of Sadat City, Sadat City, Menoufia, 32897, Egypt ...
El-Badawy MF +5 more
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Beilstein Journal of Organic Chemistry, 2019 Selectively methylated analogues of naturally occurring 2-heptyl-4(1H)-quinolones, which are alkaloids common within the Rutaceae family and moreover are associated with quorum sensing and virulence of the human pathogen Pseudomonas aeruginosa, have been
Sven Thierbach +3 more
doaj +1 more source