Results 21 to 30 of about 60,375 (278)

Disproportionality analysis of quinolone safety in children using data from the FDA adverse event reporting system (FAERS)

open access: yesFrontiers in Pediatrics, 2023
BackgroundQuinolones are widely prescribed for the treatment or prevention of infectious diseases in children. To gain further insight into quinolone-associated adverse event (AE) in children and better protect pediatric patients, continued surveillance ...
Wenqiang Kong   +4 more
doaj   +1 more source

Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients. [PDF]

open access: yes, 2012
Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used ...
Alfredo Ponce-de-Leon   +72 more
core   +8 more sources

The rates of quinolone, trimethoprim/sulfamethoxazole and aminoglycoside resistance among Enterobacteriaceae isolated from urinary tract infections in Azerbaijan, Iran

open access: yesGMS Hygiene and Infection Control, 2018
Aim: Antibiotic susceptibility patterns help to select appropriate empirical treatments of urinary tract infections (UTIs). This study aimed to investigate antibiotic resistance among Enterobacteriaceae isolated from UTIs in Azerbaijan, Iran.Methods ...
Yekani, Mina   +5 more
doaj   +1 more source

Facile access to 3-sulfonylquinolines via Knoevenagel condensation/aza-Wittig reaction cascade involving ortho-azidobenzaldehydes and β-ketosulfonamides and sulfones

open access: yesBeilstein Journal of Organic Chemistry, 2023
Quinoline-based sulfonyl derivatives, and especially sulfonamides, are relevant and promising structures for drug design. We have developed a new convenient protocol for the synthesis of 3-sulfonyl-substituted quinolines (sulfonamides and sulfones).
Ksenia Malkova   +3 more
doaj   +1 more source

Design and Synthesis of (2-oxo-1,2-Dihydroquinolin-4-yl)-1,2,3-triazole Derivatives via Click Reaction: Potential Apoptotic Antiproliferative Agents

open access: yesMolecules, 2021
A mild and versatile method based on Cu-catalyzed [2+3] cycloaddition (Huisgen-Meldal-Sharpless reaction) was developed to tether 3,3’-((4-(prop-2-yn-1-yloxy)phenyl)methylene)bis(4-hydroxyquinolin-2(1H)-ones) with 4-azido-2-quinolones in good yields ...
Essmat M. El-Sheref   +6 more
doaj   +1 more source

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis   +5 more
wiley   +1 more source

Palladium-Catalysed Synthesis and Transformation of Quinolones

open access: yesMolecules, 2019
Palladium-catalysed reactions have had a large impact on synthetic organic chemistry and have found many applications in target-oriented synthesis. Their widespread use in organic synthesis is due to the mild conditions associated with the reactions ...
Vera L. M. Silva, Artur M. S. Silva
doaj   +1 more source

Efficacy of Fluoroquinolones on Methicillin-Resistant Staphylococcus aureus Strains Isolated from External Ocular Infections [PDF]

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2023
Background and Objective: Staphylococcus aureus is one of the most common causes of bacterial keratitis and conjunctivitis. This study was done to determine the efficacy of fluoroquinolones on Methicillin-resistant Staphylococcus aureus (MRSA) strains ...
Mehri Hosseini   +2 more
doaj  

Health Risk Assessment of Antibiotic Pollutants in Large Yellow Croakers from Zhejiang Aquaculture Sites

open access: yesFoods, 2023
Intensive aquaculture combatting the decline of large yellow croaker populations can trigger bacterial outbreaks, resulting in extensive antibiotic use.
Zongjie Li   +11 more
doaj   +1 more source

Determination of Pharmaceuticals in Coastal Systems Using Solid Phase Extraction (SPE) Followed by Ultra Performance Liquid Chromatography – tandem Mass Spectrometry (UPLC-MS/MS) [PDF]

open access: yes, 2015
This paper describes the optimization and validation of an analytical method for the determination of 83 pharmaceutically active compounds (PhACs) in aqueous samples using solid-phase extraction (SPE) followed by ultra performance liquid chromatography ...
Baena Nogueras, Rosa María   +3 more
core   +1 more source

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