Results 41 to 50 of about 101,168 (296)

A Versatile Near‐Infrared Fluorescent Probe for Fast Assessment of Lysosomal Status via a Large Multimodal Model

open access: yesAggregate, EarlyView.
Herein, we report a quinolinium‐based fluorescent probe, PA‐2, for near‐infrared super‐resolution imaging of lysosomal dynamics. Building on this, we next introduce a novel approach leveraging a large multimodal model (LMM), an advanced artificial intelligence tool, for automated image interpretation.
Rui Chen   +7 more
wiley   +1 more source

Estudios de acoplamiento molecular de nuevos análogos de quinolonas a la ADN girasa de Escherichia coli [PDF]

open access: yes, 2018
Indexación: Scopus.Chemicals and CAS Registry Numbers: amino acid, 65072-01-7; ciprofloxacin, 85721-33-1; DNA topoisomerase (ATP hydrolysing); gatifloxacin, 112811-59-3, 180200-66-2; levofloxacin, 100986-85-4, 138199-71-0; lomefloxacin, 98079-51-7 ...
Davila, C.   +3 more
core  

Potentially inappropriate prescribing in nursing home residents detected with the community pharmacist specific GheOP3S-tool [PDF]

open access: yes, 2016
Background: The Ghent Older People’s Prescriptions community Pharmacy Screening (GheOP3S-)tool was recently developed to screen for potentially inappropriate prescribing (PIP).
Boussery, Koen   +7 more
core   +1 more source

Utilization, Spending, and Price Trends for Quinolones in the US Medicaid Programs: 25 Years’ Experience 1991–2015

open access: yesPharmacoEconomics - Open, 2016
BackgroundGiven that the quinolones is one of the antibacterial classes most frequently used to treat patients with bacterial infections in the United States, any change in prescribing patterns of quinolones will impact Medicaid medical expenditures ...
Z. Almalki   +4 more
semanticscholar   +1 more source

Quinolones in 2005: an update [PDF]

open access: yesClinical Microbiology and Infection, 2005
Quinolones are one of the largest classes of antimicrobial agents used worldwide. This review considers the quinolones that are available currently and used widely in Europe (norfoxacin, ciprofloxacin, ofloxacin, levofloxacin and moxifloxacin) within their historical perspective, while trying to position them in the context of recent and possible ...
Van Bambeke, Françoise   +3 more
openaire   +3 more sources

Recent Trends in Enzyme‐Based Biosensors for On‐Site Screening of Antibiotic Residues

open access: yesChemistry – An Asian Journal, EarlyView.
Antibiotic pollution pathways and biosensor intervention for effective monitoring and control of antimicrobial resistance. Abstract Antibiotics are used to treat both humans and animals for both preventive and therapeutic purposes. The overreliance on and misuse of antibiotics has given rise to a stealth pandemic, known as antimicrobial resistance (AMR)
Sapna Sudan, Bin Xie, Sunil Bhand
wiley   +1 more source

Fluoroquinolone Efficacy against Tuberculosis Is Driven by Penetration into Lesions and Activity against Resident Bacterial Populations. [PDF]

open access: yes, 2019
Fluoroquinolones represent the pillar of multidrug-resistant tuberculosis (MDR-TB) treatment, with moxifloxacin, levofloxacin, or gatifloxacin being prescribed to MDR-TB patients.
Alvarez-Cabrera, Nadine   +16 more
core   +2 more sources

Enlarged‐TriQuinoline (Enl‐TQ): Disparity in Chemical Behaviors by Geometric Scaling of the Trimeric Quinoline Ring System

open access: yesChemistry – An Asian Journal, EarlyView.
TriQuinoline (TQ), a quasi‐planar cyclic quinoline trimer in a head‐to‐tail arrangement, strongly captures a proton and exhibits unusual physicochemical properties. In this study, we designed and synthesized its expanded analog, Enlarged‐TriQuinoline (Enl‐TQ), in which three alkyne units are embedded between three quinoline units to acquire an expanded
Mai Yamashita   +3 more
wiley   +1 more source

Acute kidney injury and morbi‐mortality associated with “triple whammy” combination: Systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims “Triple whammy” (TW) refers to the concomitant use of diuretics, renin‐angiotensin‐aldosterone system inhibitors (RAASI) and non‐steroidal anti‐inflammatory drugs (NSAIDs). The aim of this article is to analyse the association between TW exposure and acute kidney injury (AKI), among other morbi‐mortality outcomes.
Dulce María Calvo   +4 more
wiley   +1 more source

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis   +5 more
wiley   +1 more source

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