Results 81 to 90 of about 60,375 (278)
Hypersensitivity reactions to quinolones
Current Opinion in Allergy & Clinical Immunology, 2011 The purpose of this review is to examine in detail the new advances in the pathomechanisms and diagnosis of immediate and nonimmediate hypersensitivity reactions to quinolones, as well as analyze cross-reactivity among different quinolones.Hypersensitivity reactions to quinolones, especially anaphylactic reactions, have become more common in the past ...
Inmaculada Andreu +2 more
openaire +4 more sources
Enantioselective Anion‐Binding‐Catalyzed Nucleophilic Addition to 4‐Quinolones
European Journal of Organic Chemistry, EarlyView.The first organocatalytic enantioselective formal 1,4‐addition to 4‐quinolones has been developed. This method relies on chiral triazole‐based anion‐binding catalysis using enol nucleophiles, complementing previous metal catalytic approaches. Moderate to good yields and enantioselectivities were achieved by in situ silylation and formation of a key ...
Martin Aleksiev +2 more
wiley +1 more source
Single-molecule observation of DNA replication repair pathways in E. coli [PDF]
arXiv, 2016 The method of action of many antibiotics is to interfere with DNA replication - quinolones trap DNA gyrase and topoisomerase proteins onto DNA while metronidazole causes single and double stranded breaks in DNA. To understand how bacteria respond to these drugs, it is important to understand the repair processes utilised when DNA replication is blocked.
arxiv
Navigating the treatment landscape of Alzheimer's disease: Current strategies and future directions
Ibrain, EarlyView.Alzheimer's disease treatment is evolving rapidly, with emerging strategies targeting multiple disease pathways. This graphical abstract highlights the shift from traditional therapies to innovative approaches that hold promise for improving outcomes.
Tapas Kumar Mohapatra +4 more
wiley +1 more source
The bactericidal activity of moxifloxacin in patients with pulmonary tuberculosis [PDF]
, 2003 Patients in whom acid-fast bacilli smear-positive pulmonary tuberculosis was newly diagnosed were randomized to receive 400 mg moxifloxacin, 300 mg isonaizid, or 600 mg rifampin daily for 5 days. Sixteen-hour overnight sputa collections were made for the
Bongard, E +7 more
core +1 more source
Investigation on Klebsiella pneumoniae in the field of extracellular vesicles
Interdisciplinary Medicine, EarlyView.The role of extracellular vesicles in the pathogenicity and antibiotic resistance, as well as treatment and prevention of Klebsiella pneumoniae. Abstract Klebsiella pneumoniae (KP), recognized for its pronounced antibiotic resistance, is a prevalent agent of nosocomial infections such as hospital‐acquired pneumonia.
Junwei Wu +10 more
wiley +1 more source
Usual and unusual antibacterial effects of quinolones [PDF]
, 2017 Recently documented antibacterial effects of quinolones are reviewed. DNA gyrase is most likely to be the primary target site for these agents. Quinolones rapidly kill susceptible bacteria; the mechanisms of the bactericidal activity, still poorly ...
Furet, Y. X., Pechère, J.-C
core
Journal of Clinical Laboratory Analysis, EarlyView.E. faecalis was the predominant species (60.7%). Moreover, 39.3% of the isolates were identified as VRE with an MIC > 32 μg/mL, and the vanA gene was detected in 35.7% of the isolates. High‐level resistance to gentamicin and streptomycin was observed in 60.7% and 50% of the isolates, respectively.
Maryam Koleini +3 more
wiley +1 more source
Uso y abuso del ciprofloxacino Ciprofloxacin use and overuse
Medisan, 2011 Las quinolonas son antibacterianos eficaces contra gérmenes gramnegativos y especialmente útiles para eliminar infecciones de las vías urinarias u otras localizaciones, así como también para tratar a pacientes con enfermedades de transmisión sexual.
Abel Tobías Suárez Olivares +1 more
doaj
Medicina Veterinária, 2021 This study aimed to identify which are the most frequent bacteria evolved in cases of chronic otitis in dogs in the metropolitan region of Curitiba, as well to determine their in vitro antimicrobial susceptibility.
Jorge Bárcena Barriuso +6 more
doaj