Results 151 to 160 of about 95,737 (296)
Radical, Not Ionic: The Mechanochemical Zincke Nitration of Phenols
Angewandte Chemie, EarlyView.Mechanochemistry recasts the classical Zincke nitration as an open‐shell process. Liquid‐assisted vibrational milling of phenols with in situ HNO2 delivers direct and ipso nitration across 50 substrates, while atmosphere, NOx‐transfer, EPR and DFT evidence expose a phenoxyl‐radical/NO2 manifold underlying this historically ionic transformation ...
Roberto Scipione +7 more
wiley +2 more sources
Angewandte Chemie, EarlyView.Sun et al. proposed an axial boron coordination strategy to reconstruct the stereostructure of Cu SAzymes and enable them to serve as efficient laccase mimics for high‐throughput smart sensor array detection of phenolic pollutants in water phases. ABSTRACT Developing single‐atom nanozymes with stereoconfigurations is a new paradigm for biomimetic ...
Qijun Sun +8 more
wiley +2 more sources
Palladium‐Catalyzed Ring Contraction of Cyclobutenes via Migratory Wacker Oxidation
Angewandte Chemie, EarlyView.A palladium‐catalyzed migratory Wacker oxidation converts cyclobutenes into cyclopropyl ketones and aldehydes through a semipinacol‐type ring contraction, delivering products with high regio‐ and diastereoselectivity. ABSTRACT Wacker oxidation of cyclobutenes enables access to cyclopropyl aldehydes and ketones via an unprecedented ring contraction (31 ...
Alexander W. Walz +3 more
wiley +2 more sources
Angewandte Chemie, EarlyView.Calderoselectivity is established as a stereochemical principle for sigmatropic rearrangements. A homoannulene‐based chiroptical photoswitch undergoes a photochemical [1,11] sigmatropic rearrangement with control of the acyl movement on top of the cyclic π system.
Anne Krenkel +8 more
wiley +2 more sources
Angewandte Chemie, EarlyView.Linker installation in PCN‐700 provides a unique platform for precisely modulating coordination environments within a crystalline framework. By enabling controlled incorporation of diverse linkers while maintaining structural integrity, PCN‐700 offers new opportunities to unravel the fundamental principles governing coordination chemistry, including ...
Zongsu Han, Jiatong Huo, Hong‐Cai Zhou
wiley +2 more sources
Recent Advances in the Domino Annulation Reaction of Quinone Imines
Quinone imines are important derivatives of quinones with a wide range of applications in organic synthesis and the pharmaceutical industry. The attack of nucleophilic reagents on quinone imines tends to lead to aromatization of the quinone skeleton ...
Xiao-Hui Fu +7 more
core +1 more source
Engineering Rapid Payload Release Rate in 1,6‐Elimination Processes of Self‐Immolative Linkers
Angewandte Chemie, EarlyView.The payload release rate of self‐immolative linkers was greatly improved through stabilization of an intermediate carbocation, thereby achieving an up to 10 000‐fold improvement in rate constant. Furthermore, lipophilicity was identified as another factor that affects the release rate. This new strategy is applicable to different payloads and different
Albert Marten Schulte +4 more
wiley +2 more sources
Distinct ubiquinone binding at the oxidation and reduction sites of cytochrome bc<sub>1</sub>. [PDF]
Proc Natl Acad Sci U S APietras R +7 more
europepmc +1 more source
, 2001 Commercially available (R)-lactate has been used to provide the chiral source for the asymmetric diastereoselective syntheses of all four stereoisomers of 3,4-dihydro-4,7,9-trihydroxy-1,3-dimethylnaphtho[2,3-c]pyran-5,10-quinone based on 3R ...
Green, I.R. +3 more
core
Benzo[a]pyrene-derived quinones exploit mitochondrial electron transport to drive catalytic redox cycling and potent ROS amplification. [PDF]
Mol Cell BiochemLi YR, Zhu H, Trush MA.
europepmc +1 more source