Results 1 to 10 of about 166,984 (347)
Efficient and selective N-alkylation of amines with alcohols catalysed by manganese pincer complexes
Nature Communications, 2016 Hydrogen borrowing is an attractive method for C-N bond formation - avoiding multiple alkylation products and reducing waste - but often is carried out with noble metals.
Saravanakumar Elangovan +5 more
doaj +2 more sources
DNA Alkylation Damage by Nitrosamines and Relevant DNA Repair Pathways
International Journal of Molecular Sciences, 2023 Nitrosamines occur widespread in food, drinking water, cosmetics, as well as tobacco smoke and can arise endogenously. More recently, nitrosamines have been detected as impurities in various drugs.
J. Fahrer, M. Christmann
semanticscholar +1 more source
Copper-Catalyzed Enantioconvergent Alkylation of Oxygen Nucleophiles
Nature, 2023 Carbon–oxygen bonds are commonplace in organic molecules, including chiral bioactive compounds; therefore, the development of methods for their construction with simultaneous control of stereoselectivity is an important objective in synthesis.
Caiyou Chen, G. Fu
semanticscholar +1 more source
Ketone α-alkylation at the more-hindered site
Nature Communications, 2023 Control of the regioselectivity of α-alkylation of carbonyl compounds is a longstanding topic of research in organic chemistry. By using stoichiometric bulky strong bases and carefully adjusting the reaction conditions, selective alkylation of ...
Ming-Ming Li +6 more
doaj +1 more source
Versatile cell-based assay for measuring DNA alkylation damage and its repair
Scientific Reports, 2021 DNA alkylation damage induced by environmental carcinogens, chemotherapy drugs, or endogenous metabolites plays a central role in mutagenesis, carcinogenesis, and cancer therapy.
Yong Li +5 more
doaj +1 more source
Journal of the American Chemical Society, 2022 Sulfoximines are increasingly incorporated in agrochemicals and pharmaceuticals with the two enantiomers of chiral sulfoximines often having profoundly different binding interactions with biomolecules.
Nathaniel S. Greenwood +2 more
semanticscholar +1 more source
Nature Communications, 2023 C−C bond forming reaction by alkylation of aryl rings is a main pillar of chemistry in the production of broad portfolios of chemical products. The dominant mechanism proceeds via electrophilic substitution of secondary and tertiary carbocations over ...
Xinze Du +3 more
doaj +1 more source
Green Energy & Environment, 2022 Side-chain alkylation of toluene with methanol is a green pathway to realize the one-step production of styrene under mild conditions, but the low selectivity of styrene is difficult to be improved with by-products of ethylbenzene and xylene.
Zhe Hong +4 more
doaj +1 more source
Alkylation of Dihydrofullerenes [PDF]
The Journal of Organic Chemistry, 2002 The fulleride dianions C(60)(2-) and C(70)(2-) were generated by deprotonation of the corresponding hydrogenated fullerenes, 1,2-C(60)H(2) and 1,2-C(70)H(2). These anions were prepared in the presence of a variety of alkylating agents, and mono- or dialkylated products were obtained. Alkylation was not successful with sulfonate ester alkylating agents.
Mark S, Meier +4 more
openaire +2 more sources
Heterocyclic Communications, 2021 This mini-review encapsulates the latest findings (past 10 years) in the field of the deep eutectic solvents (DESs) application in the alkylation/arylation of different heterocyclic compounds.
Molnar Maja +4 more
doaj +1 more source