Cu-catalyzed Asymmetric Alkylation for Chiral Unnatural α-Substituted α-Amino Acids of Phallotoxins [PDF]
, 2023 Asymmetric alkylation is one of the most important methods for synthesizing chiral unnatural α-substituted α-amino acids. Herein, We reported an asymmetric alkylation of tert-butyl glycinate Schiff base catalyzed by copper/(4S,2R)-tBu-Phosferrox ...
Yang, Wang +6 more
core +2 more sources
Biochemical characterization and DNA repair pathway interactions of Mag1-mediated base excision repair in Schizosaccharomyces pombe [PDF]
, 2005 The Schizosaccharomyces pombe mag1 gene encodes a DNA repair enzyme with sequence similarity to the AlkA family of DNA glycosylases, which are essential for the removal of cytotoxic alkylation products, the premutagenic deamination product hypoxanthine ...
Alseth, I +8 more
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Redox-Neutral Synthesis of Sulfilimines through the S-Alkylation of Sulfenamides [PDF]
, 2023 Sulfilimines are a class of bioisosteres with immense potential in medicinal chemistry, characterized by the presence of a tetravalent sulfur atom bearing one nitrogen and two distinct carbon substitutes.
Xunbo, Lu +3 more
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Regioselective Alkylation of an Oxonaphthalene-Annelated Pyrrol System
Molbank, 2009 The regioselective alkylation of an oxonaphthalene-annelated pyrrole system is reported. The regioselectivity of alkylation can be controlled by the selection of the solvent.
Helmut Spreitzer, Christiane Puschmann
doaj +1 more source
Heterogeneous Friedel–Crafts Alkylation
, 2023 Heterogeneous alkylation of arene and related catalysis are overviewed from industrial and academic aspects. We first discuss, principally from industrial aspects, the synthesis of ethylbenzene (EB) and cumene (IPB) by the alkylation of benzene using ...
Nishimura, Y +4 more
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Synthesis of tetrahydrokhusitone: Annulation of the cyclohexane ring by free radical and carbanionic sequence of reactions [PDF]
Journal of the Serbian Chemical Society, 2003 The synthesis of norcadinane sesquiterpene tetrahydrokhusitone 1 has been achieved by a new method for annulation of cyclohexane ring involving a sequence of free radical δ-alkylation of the non-activated carbon atom and intramolecular carbanionic ...
Petrović Goran, Čeković Živorad
doaj +1 more source
3-(2-Diisopropylaminoethyl)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione
Molbank, 2022 Thiazolidine-2,4-dione core is widely used in the medicinal chemistry of different types of potential drug-like small molecules. In the present work, the synthesis of a novel non-condensed thiazolidine-2,4-dione-bearing derivative is reported by the two ...
Serhii Holota +3 more
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C–H Alkylation of Cubanes via Polar Effect-Assisted Photocatalytic Generation of Cubyl Radicals [PDF]
, 2023 A method for C–H alkylation of cubanes is described herein. A hydrogen atom–transfer catalyst enables direct abstraction of a hydrogen atom from the C–H bond of cubanes, followed by conjugate addition of the generated cubyl radicals to various Michael ...
Masaki, Hosaka +2 more
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Meitan kexue jishu, 2023 Coal-tar pitch (CTP) is a substance produced by ambient and/or vacuum distillation of high-temperature coal tar, although CTP has a large yield in China, however its wide application is limited due to its high toxicity.
ZHANG Wenshuo +5 more
doaj +1 more source
Selective C(sp3)–H Arylation/Alkylation of Alkanes Enabled by Paired Electrocatalysis [PDF]
, 2023 We report a combination of electrocatalysis and photoredox catalysis to perform selective C(sp3)–H arylation/alkylation of alkanes for the first time, in which a binary catalytic system based on earth-abundant iron and nickel is applied.
Rui, Sun +3 more
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