Alkyl–Alkyl Suzuki Cross‐Coupling of Unactivated Secondary Alkyl Chlorides [PDF]
Angewandte Chemie, 2010 The first method for achieving alkyl–alkyl Suzuki reactions of unactivated secondary alkyl chlorides has been developed. Carbon–carbon bond formation occurs under mild conditions (at room temperature) with the aid of commercially available catalyst components.
Lu, Zhe, Fu, Gregory C.
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DNA polymerase α (swi7) and the flap endonuclease fen1 (rad2) act together in the s-phase alkylation damage response in S. pombe [PDF]
, 2012 Polymerase α is an essential enzyme mainly mediating Okazaki fragment synthesis during lagging strand replication. A specific point mutation in Schizosaccharomyces pombe polymerase α named swi7-1, abolishes imprinting required for mating-type switching ...
Koulintchenko Milana +20 more
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Alkylation of Magnesium Enamide with Alkyl Chlorides and Fluorides. [PDF]
ChemInform, 2005 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Takuji, Hatakeyama +3 more
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New catalytic strategies for DNA and RNA alkylation using rhodium (II) and copper (I) carbenes - a versatile tool for applications in chemical biology [PDF]
, 2015 A variety of nucleic acid substrates were catalytically alkylated with rhodium(II) and copper(I)-carbenoids generated from diazocarbonyl compounds. The alkylation took place via an N-H insertion reaction selectively targeting the nucleobases in single ...
Tishinov, Kiril
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Redox-Neutral Synthesis of Sulfilimines through the S-Alkylation of Sulfenamides [PDF]
, 2023 Sulfilimines are a class of bioisosteres with immense potential in medicinal chemistry, characterized by the presence of a tetravalent sulfur atom bearing one nitrogen and two distinct carbon substitutes.
Xunbo, Lu +3 more
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Catalytic Asymmetric Reductive Alkylation of Enamines to Chiral Aliphatic Amines [PDF]
, 2020 Herein, we report a mild and general nickel-catalysed asymmetric reductive alkylation to effectively convert enamines—a class of important yet underexploited feedstock chemicals—into drug-like α-branched chiral amines and derivatives.
Jia-Wang, Wang +7 more
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Catalytic Photochemical Enantioselective α-Alkylation with Pyridinium Salts [PDF]
, 2022 We have developed a chiral amine catalyzed enantioselective α-alkylation of aldehydes with amino acid derived pyridinium salts as alkylating reagents. The reaction proceeds in the presence of visible light (390 nm) and in the absence of a photocatalyst ...
Santhivardhana Reddy, Yetra +5 more
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3-(2-Diisopropylaminoethyl)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione
Molbank, 2022 Thiazolidine-2,4-dione core is widely used in the medicinal chemistry of different types of potential drug-like small molecules. In the present work, the synthesis of a novel non-condensed thiazolidine-2,4-dione-bearing derivative is reported by the two ...
Serhii Holota +3 more
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Homogeneous Friedel–Crafts Alkylation
, 2023 Since its discovery in 1877, Friedel–Crafts alkylation has been one of the most significant reactions in organic chemistry. The breadth of this reaction has increased over 130 years, and it is now moving toward a more environmental friendly and ...
Dasireddy, VDBC +9 more
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Meitan kexue jishu, 2023 Coal-tar pitch (CTP) is a substance produced by ambient and/or vacuum distillation of high-temperature coal tar, although CTP has a large yield in China, however its wide application is limited due to its high toxicity.
ZHANG Wenshuo +5 more
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