Synthesis of Secondary Amines via Self-Limiting Alkylation of N-Aminopyridinium Salts [PDF]
, 2023 Partial amine alkylation to prepare secondary amines is challenging due to the enhanced N-nucleophilicity that accompanies alkylation. Here we introduce N-aminopyridinium salts as ammonia surrogates for the synthesis of secondary amines via self-limiting
David, Powers +4 more
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Iridium-Catalyzed Enantioselective Formal α-Allylic Alkylation of Acrylonitrile [PDF]
, 2023 A highly enantioselective formal α-allylic alkylation of acrylonitrile is developed using 4-cyano-3-oxotetrahydrothiophene (c-THT) as a safe and easy-to-handle surrogate of acrylonitrile.
Pankaj, Roy, Santanu, Mukherjee
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Enantioselective Synthesis of Skipped Dienes via Iridium-Catalyzed Allylic Alkylation of Phosphonate Carbanions [PDF]
, 2022 An enantioselective synthesis of skipped diene has been developed based on an iridium-catalyzed allylic alkylation of phosphonate carbanions and Horner-Wadsworth-Emmons olefination.
Arko, Seal, Santanu, Mukherjee
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Alkylation of Dihydrofullerenes [PDF]
The Journal of Organic Chemistry, 2002 The fulleride dianions C(60)(2-) and C(70)(2-) were generated by deprotonation of the corresponding hydrogenated fullerenes, 1,2-C(60)H(2) and 1,2-C(70)H(2). These anions were prepared in the presence of a variety of alkylating agents, and mono- or dialkylated products were obtained. Alkylation was not successful with sulfonate ester alkylating agents.
Mark S, Meier +4 more
openaire +2 more sources
Catalytic Friedel–Crafts Reactions of Unactivated Secondary Alcohols: Site-Selective ortho-Alkylation of Phenols [PDF]
, 2023 A combination of catalytic ZnCl2 and catalytic CSA enables the first site-selective Friedel–Crafts alkylation of phenolic derivatives with unactivated secondary alcohols.
Kevin, Kou +4 more
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Nickel-Catalyzed Reductive Alkylation of Heteroaryl Imines [PDF]
, 2022 A Ni-catalyzed reductive cross-coupling of heteroaryl imines with C(sp3) electrophiles for the preparation of heterobenzylic amines is reported. This umpolung-type alkylation proceeds under mild conditions, avoids the pre-generation of organometallic ...
Marco, Brandstätter +5 more
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Nickel-catalyzed C-alkylation of nitroalkanes with alkyl halides
, 2022 Watson, Donald A.This dissertation focuses on the development of novel methods for nickel-catalyzed C-alkylation of nitroalkanes and mechanistic studies of them.
Rezazadeh, Sina
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Iridium-Catalyzed Asymmetric α-Allylic Alkylation of Amides using Vinyl Azide as Amide Enolate Surrogate [PDF]
, 2020 Among the unstabilized enolates used as nucleophile in iridium-catalyzed asymmetric allylic alkylation reactions, amide enolates are least explored. Vinyl azides are now employed as amide enolate surrogate for the first time in Ir-catalyzed asymmetric ...
Aditya, Chakrabarty, Santanu, Mukherjee
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Selective C(sp3)–H Arylation/Alkylation of Alkanes Enabled by Paired Electrocatalysis [PDF]
, 2023 We report a combination of electrocatalysis and photoredox catalysis to perform selective C(sp3)–H arylation/alkylation of alkanes for the first time, in which a binary catalytic system based on earth-abundant iron and nickel is applied.
Rui, Sun +3 more
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C–H Alkylation of Cubanes via Polar Effect-Assisted Photocatalytic Generation of Cubyl Radicals [PDF]
, 2023 A method for C–H alkylation of cubanes is described herein. A hydrogen atom–transfer catalyst enables direct abstraction of a hydrogen atom from the C–H bond of cubanes, followed by conjugate addition of the generated cubyl radicals to various Michael ...
Masaki, Hosaka +2 more
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