Results 41 to 50 of about 1,291 (216)

Narrative Review: Quintuple Helixs Model for Malaria Elimination in Indonesia

open access: yesJurnal Kesehatan Mahardika, 2022
Malaria continues to impact the health and economies of people around the world. Further steps need to be taken in accordance with the Global Technical Strategy for malaria to prevent malaria transmission. Quintuple helix model is an integrated effort that involves cross-sector in controlling malaria cases in an area.
Yura Witsqa Firmansyah   +13 more
openaire   +1 more source

Mapping the helix model of innovation influence on education: A bibliometric review

open access: yesFrontiers in Education, 2023
As a direct result of the increased significance of knowledge in the various endeavours attempting to implement the triple helix model, higher education institutions have assumed a more prominent position in the processes involved in regional innovation ...
Haziman Zakaria   +3 more
doaj   +1 more source

Methodological approach of investment and innovation regional environmental policy using the smart specialization and quintuple helix models

open access: yesEconomics and Environment, 2021
The purpose of the study, therefore, is to form a methodological approach сoncerning the determination of dominants of investment and innovation regional environmental policy.
Natalya Andryeyeva   +4 more
doaj  

Extension of the Triple Helix to Quadruple to Quintuple Helix Model

open access: yesJournal of APF Command and Staff College
This study explores the multiple helices extended from the Triple Helix (TH) Model of innovation. Describing what Triple Helix, Quadruple Helix and Quintuple Helix Model as well as and Mode3 is the primary motive of this paper. This study is solely based on secondary sources and the research is exploratory as well as descriptive in its nature ...
Ramesh Raj Kunwar, Nimesh Ulak
openaire   +1 more source

The Quintuple Helix Model and the Future of Mobility: The role of Autonomous Vehicles in a Developing Country

open access: yesRevista de Administração, Sociedade e Inovação, 2020
Este artigo descritivo, de abordagem qualitativa, teve como objetivo compreender se o Modelo Quíntuplo de Hélice (MQH) pode promover positivamente avanços na mobilidade urbana a partir da inserção dos Veiculos Autônomos (VAs) na sociedade, bem como ...
Rodrigo Marçal Gandia   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Enzymatic Encoding of Topology in an Intrinsically Disordered Single‐Chain Protein

open access: yesAngewandte Chemie, EarlyView.
Enzymatic intramolecular cross‐linking enables topology control in intrinsically disordered proteins, yielding SCNPs with reproducible cavity architectures. Using β‐casein and microbial transglutaminase, sparse, sequence‐resolved constraints drive compact collapse without inducing secondary structure.
Joshua Johani   +9 more
wiley   +2 more sources

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

STRATEGIC MANAGEMENT OF INVESTMENT AND INNOVATION ACTIVITIES IN THE FIELD OF ENVIRONMENTALLY SAFE LAND MANAGEMENT

open access: yesEconomics and Environment, 2021
The purpose of the study is to form a methodology for strategic management of investment and innovation activities in environmentally safe nature management based on the analysis of world experience.
Анна Тютюнник   +2 more
doaj   +1 more source

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