Results 51 to 60 of about 108,619 (175)

AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes

Advanced Intelligent Discovery, EarlyView.
To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song, Xinmin Li, Hongbo Yu, Le Xiong, Guixia Liu, Weihua Li, Yun Tang   +6 more
wiley   +1 more source

Moving to a quintuple helix approach in SPP

, 2019
Sustainability is aimed at addressing environmental and socio-economic issues of this generation and future ones. Sustainability requires the engagement of stakeholders, as highlighted by Agenda 21 where stakeholder engagement and participation in ...
Lozano, Rodrigo,, Sigrid Petterssén, Petterssén, S., Jonsäll, Anette, Björn Bergström, Rodrigo Lozano, Niss, Camilla,, Anette Jonsäll, Bergström, B., Camilla Niss   +9 more
core   +1 more source

What factors influence research impact? An empirical study on the interplay of research, publications, researchers, institutions, and national conditions

Journal of Data and Information Science
This study investigates key factors contributing to research impact and their interactions with the Research Impact Quintuple Helix Model by Arsalan et al. (2024).
Arsalan Mudassar Hassan, Mubin Omar, Mahmud Abdullah Al, Perveen Sajida   +3 more
doaj   +1 more source

Governance and Quintuple Helix innovation model: Insights from the local government of East Luwu Regency, Indonesia

Frontiers in Climate, 2022
Climate change issues pose complex social and ecological challenges to rural communities in East Luwu Regency, Indonesia. This can be overcome through a collaborative, sustainable, and distributed innovation process for regional resilience and ...
Abdillah Abdillah, Abdillah Abdillah, Ida Widianingsih, Rd Ahmad Buchari, Nuryanti Mustari, Syafiuddin Saleh   +5 more
doaj   +1 more source

Integration of Liquid Handling Robotics, Turbidimetry, and Machine Learning Toward Inverse Design of Lower Critical Solution Temperature Polymer Formulations

Advanced Intelligent Systems, EarlyView.
An integrated OT‐2/plate reader platform automates LCST cloud point measurement of NIPAM‐co‐DMAEMA copolymers across high‐dimensional formulation spaces. Machine learning trained on the resulting high‐throughput datasets achieves R2 up to 0.96 and enables inverse design of polymer formulations to target transition temperatures with <1% error.
Lachlan Alexander, Vianna F. Jafari, Tanja Junkers   +2 more
wiley   +1 more source

Governing sustainable urban brownfield redevelopment in China: Applying the Quintuple Helix model in Chengdu

Ain Shams Engineering Journal
This study examines sustainable urban brownfield redevelopment through the Quintuple Helix Model, encompassing universities, government, industry, civil society, and the environment. A structured survey of 436 respondents across five districts in Chengdu,
Dan He, Huizi Deng, Yunlong Niu, Jun Li, Rosilawati Zainol, Nor Shahida Azali   +5 more
doaj   +1 more source

Enhancing Adeno‐Associated Virus 2 Capsid Engineering Through Co‐Evolutionary Coupling

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated virus (AAV) has emerged as a leading platform for gene therapy. However, to unlock the full potential, their manufacturing yields, stability, and efficacy must all be improved. Rational design is limited by poor predictability and the potential impact of mutations on multiple important vector properties.
Sirimar Laosinwattana, Yiwen Li, Braulio Carrillo Sanchez, Ayesha Khan, Paul A. Dalby   +4 more
wiley   +1 more source

Determinants of Climate Change Disclosure by Central Governments: Exploratory Research Through Sustainable Development Goal 13

Business Strategy and the Environment, EarlyView.
ABSTRACT This research examines the extent of voluntary climate change disclosure by central governments worldwide through Sustainable Development Goal (SDG) 13 targets and analyzes determinants that may influence this disclosure. Using qualitative and quantitative methods, a content analysis of SDG13 and its targets was applied to the voluntary ...
Ferdinando Di Carlo, Manuela Lucchese, Silvia Solimene, Valery Rago   +3 more
wiley   +1 more source

Assessing the Impact of a Quintuple Helix Framework on Smart City Performance: A Country-Level Analysis of EU Capitals

Urban Science
Although Smart City transitions are typically assessed using technological and financial indicators, the underlying structural correlates remain insufficiently explored.
Erika Loučanová, Miriam Olšiaková, Florin Cornel Dumiter, Marius Boiță   +3 more
doaj   +1 more source

How Institutional Environments Shape the ESG–Growth Relation: Evidence From Europe

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT As global financial markets increasingly integrate non‐financial criteria, companies are reinforcing the strategic role of sustainability and its impact on market value, although this cannot overlook how different institutional structures shape investor perceptions.
Laura Bango‐López, Cristina Gutiérrez‐López, Paula Castro, María Belén Lozano‐García   +3 more
wiley   +1 more source