Results 71 to 80 of about 13,920,974 (215)

Integration of Liquid Handling Robotics, Turbidimetry, and Machine Learning Toward Inverse Design of Lower Critical Solution Temperature Polymer Formulations

Advanced Intelligent Systems, EarlyView.
An integrated OT‐2/plate reader platform automates LCST cloud point measurement of NIPAM‐co‐DMAEMA copolymers across high‐dimensional formulation spaces. Machine learning trained on the resulting high‐throughput datasets achieves R2 up to 0.96 and enables inverse design of polymer formulations to target transition temperatures with <1% error.
Lachlan Alexander, Vianna F. Jafari, Tanja Junkers   +2 more
wiley   +1 more source

Initial actions of the Brazilian regional innovation ecosystem against the COVID-19 pandemic

International Journal of Innovation, 2022
Objective: We have analyzed Brazil’s initial COVID-19 combat actions by the regional innovation ecosystem actors. Methodology/approach: This is a descriptive and qualitative study using documentary research.
Newton da Silva Miranda Junior, Luiz Fernando Câmara Viana, Dayse Karenine de Oliveira Carneiro, Renan Costa Filgueiras, Gislayne da Silva Goulart   +4 more
doaj   +1 more source

Helix trilogy: the Triple, Quadruple, and Quintuple Innovation Helices from a theory, policy, and practice set of perspectives

, 2022
Summarization: For an understanding of the concept of the Quadruple and Quintuple Helix Innovation Systems, it is essential to realize that the Quadruple and Quintuple Helices are based on democracy and ecology. This has two implications: (1) the further
Carayannis, Elias G(https://viaf.org/viaf/229482869), Campbell David F. J., Grigoroudis Evangelos(http://users.isc.tuc.gr/~egrigoroudis), Γρηγορουδης Ευαγγελος(http://users.isc.tuc.gr/~egrigoroudis)   +3 more
core   +1 more source

Civic university model as living lab : potential and challenges

Multidisciplinary Adaptive Climate Insights
To construct a dynamic model inside the university that emphasizes its position within society and expedites sustainable development goals, this article discusses the civic university and how it can benefit from emerging concepts like the Living Lab and ...
Rania Rageh
doaj   +1 more source

Enhancing Adeno‐Associated Virus 2 Capsid Engineering Through Co‐Evolutionary Coupling

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated virus (AAV) has emerged as a leading platform for gene therapy. However, to unlock the full potential, their manufacturing yields, stability, and efficacy must all be improved. Rational design is limited by poor predictability and the potential impact of mutations on multiple important vector properties.
Sirimar Laosinwattana, Yiwen Li, Braulio Carrillo Sanchez, Ayesha Khan, Paul A. Dalby   +4 more
wiley   +1 more source

Determinants of Climate Change Disclosure by Central Governments: Exploratory Research Through Sustainable Development Goal 13

Business Strategy and the Environment, EarlyView.
ABSTRACT This research examines the extent of voluntary climate change disclosure by central governments worldwide through Sustainable Development Goal (SDG) 13 targets and analyzes determinants that may influence this disclosure. Using qualitative and quantitative methods, a content analysis of SDG13 and its targets was applied to the voluntary ...
Ferdinando Di Carlo, Manuela Lucchese, Silvia Solimene, Valery Rago   +3 more
wiley   +1 more source

Facilitating Quintuple helix innovation with urban living labs [PDF]

, 2015
This paper discusses the Urban Living Lab approach as a way to put the Quintuple Helix model for innovation into practice. In this analysis we focus on the concepts innovation democracy, ‘mode 3’ knowledge production, the innovation ecosystem as a system
Schuurman, Dimitri, Baccarne, Bastiaan, De Marez, Lieven   +2 more
core  

Fostering Work Readiness in Gen Z through Quintuple Helix, 4P's Creativity

Jurnal Aplikasi Manajemen
This study aims to explore gender differences in creativity exploration and work readiness among Generation Z employees in the workplace. It integrates the Quintuple Helix model with the 4P's creativity model to comprehensively understand how gender ...
Ilzar Daud, Melia Wida Rahmayani, Syahrul Nugraha, Wayan Suryathi, Danny Hidayat   +4 more
doaj   +1 more source

MurNAc‐Based Electrophilic Inhibitors of O‐Acetylpeptidoglycan Esterase (Ape): Design, Synthesis, and Kinetic Evaluation

Chemistry – A European Journal, EarlyView.
A series of N‐acetylmuramic acid (MurNAc)‐based electrophilic inhibitors targeting Ape esterase was synthesized. Their inhibitory potency ranged from micromolar to submillimolar. The study probed binding contributions of stem peptide extension, replacing the anomeric methyl group with a benzyl, and α‐fluorination of the carbonyl to enhance ...
Dmytro Voskoboinyk, Martin E. Tanner
wiley   +1 more source

use of modified quintuple helix innovation model

, 2020
Life Cycle Assessment (LCA) is identified as a systematic analytical tool used to assess the total environmental burdens related to any product, process, or activity by assessing all upstream flows and all downstream flows throughout the whole value ...
Amarasinghe SDIA
core