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Experimental and theoretical study on the substitution reactions of aryl 2,4-dinitrophenyl carbonates with quinuclidines [PDF]
Tetrahedron, 2006 The reactions of quinuclidines with phenyl, 4-methylphenyl, and 4-chlorophenyl 2,4-dinitrophenyl carbonates are kinetically evaluated in aqueous solution. The Bronsted-type plots (log k(N) vs pK(a) of quinuclidinium ions) are linear. The magnitude of the
Renato Contreras +2 more
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Stereochemistry of benzo[b]quinuclidines
Chemistry of Heterocyclic Compounds, 1972A D Yanina, E E Mikhlina
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The synthesis and application of functionalised quinuclidines [PDF]
, 2005 EThOS - Electronic Theses Online ServiceGBUnited ...
Hitchin, James Richard
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Discovery of quinuclidine modulators of cellular progranulin
Bioorganic & Medicinal Chemistry Letters, 2021Phenotypic screening of an annotated small molecule library identified the quinuclidine tetrahydroisoquinoline solifenacin (1) as a robust enhancer of progranulin secretion with single digit micromolar potency in a murine microglial (BV-2) cell line.
James C. Lanter +5 more
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Chemistry of quinuclidines as nitrogen bicyclic bridged-ring structures
Journal of Heterocyclic Chemistry, 2006 Wafaa Salama Hamama, Hanafi Zoorob
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THE CHEMISTRY OF QUINUCLIDINE DERIVATIVES
Russian Chemical Reviews, 1960CONTENTS I. Introduction 38 II. Quinuclidine 38 III.
M V Rubtsov, E E Mikhlina, L N Yakhontov
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Russian Chemical Reviews, 1969
The review deals with the chemical properties and the biological activity of the derivatives of 1-azabicyclo[2,2,2]octane widely known as quinuclidine. The work of the Soviet School of Chemists, founded by M.V.Rubtsov, in the field of quinuclidine derivatives is reviewed in detail.
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The review deals with the chemical properties and the biological activity of the derivatives of 1-azabicyclo[2,2,2]octane widely known as quinuclidine. The work of the Soviet School of Chemists, founded by M.V.Rubtsov, in the field of quinuclidine derivatives is reviewed in detail.
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Tetrahedron Letters, 2008
Lithiation of 3-methoxymethyl quinuclidine N-oxide occurs regioselectively to generate the 2-lithio 3-methoxymethyl derivative which can be trapped out with non-enolisable electrophiles to give 2,3-disubstituted quinuclidine N-oxide derivatives in good yield.
Ian A. O’Neil +4 more
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Lithiation of 3-methoxymethyl quinuclidine N-oxide occurs regioselectively to generate the 2-lithio 3-methoxymethyl derivative which can be trapped out with non-enolisable electrophiles to give 2,3-disubstituted quinuclidine N-oxide derivatives in good yield.
Ian A. O’Neil +4 more
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Chemischer Informationsdienst, 1978
AbstractDie Chinuclidin‐2‐ (II) und ‐3‐carbonsäureamide (III) wurden durch Kondensation des Säurechlorids (I) bzw. des isomeren 3‐Chlorcarbonyl‐Derivats mit den entsprechenden Aminen erhalten.
S. BINIECKI, B. PROKOPCZYK
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AbstractDie Chinuclidin‐2‐ (II) und ‐3‐carbonsäureamide (III) wurden durch Kondensation des Säurechlorids (I) bzw. des isomeren 3‐Chlorcarbonyl‐Derivats mit den entsprechenden Aminen erhalten.
S. BINIECKI, B. PROKOPCZYK
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