Results 111 to 120 of about 1,080 (176)

Rapid Affinity and Microsomal Stability Ranking of Crude Mixture Libraries of Histone Deacetylase Inhibitors. [PDF]

open access: yesACS Med Chem Lett
Tyagarajan S   +22 more
europepmc   +1 more source

Treatment of xerostomia in Sjögren's syndrome - what effect does it have on the oral microbiome? [PDF]

open access: yesFront Cell Infect Microbiol
Muszyński D   +7 more
europepmc   +1 more source

Economic Analysis of New Single-Inhaler Triple Therapies in Patients with COPD in the UK. [PDF]

open access: yesInt J Chron Obstruct Pulmon Dis
Cai R   +7 more
europepmc   +1 more source

Stereochemistry of benzo[b]quinuclidines

Chemistry of Heterocyclic Compounds, 1973
V Ya Vorob'Eva
exaly   +3 more sources

Stereochemistry of benzo[b]quinuclidines

Chemistry of Heterocyclic Compounds, 1972
A D Yanina
exaly   +2 more sources

Discovery of quinuclidine modulators of cellular progranulin

Bioorganic & Medicinal Chemistry Letters, 2021
Phenotypic screening of an annotated small molecule library identified the quinuclidine tetrahydroisoquinoline solifenacin (1) as a robust enhancer of progranulin secretion with single digit micromolar potency in a murine microglial (BV-2) cell line.
James C. Lanter   +5 more
openaire   +2 more sources

Directed lithiation on the quinuclidine ring system: the synthesis of 2,3-difunctionalised quinuclidines

Tetrahedron Letters, 2008
Lithiation of 3-methoxymethyl quinuclidine N-oxide occurs regioselectively to generate the 2-lithio 3-methoxymethyl derivative which can be trapped out with non-enolisable electrophiles to give 2,3-disubstituted quinuclidine N-oxide derivatives in good yield.
Ian A. O’Neil   +4 more
openaire   +1 more source

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