Durable formulations of quorum quenching enzymes [PDF]
Scientific ReportsEnzymes with industrial potential often face limitations due to stability and longevity constraints. Thermostable quorum quenching lactonases are appealing biotechnology tools for controlling microbial pathogenicity and biofilm formation via the ...
Reed Jacobson +2 more
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The quorum quenching enzyme Aii20J modifies in vitro periodontal biofilm formation. [PDF]
Front Cell Infect Microbiol, 2023 Introduction Recent studies have revealed the presence of N-acyl-homoserine lactones (AHLs) quorum sensing (QS) signals in the oral environment. Yet, their role in oral biofilm development remains scarcely investigated.
Parga A +9 more
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Quorum Quenching Approaches against Bacterial-Biofilm-Induced Antibiotic Resistance [PDF]
AntibioticsWith the widespread phenomenon of antibiotic resistance and the diffusion of multiple drug-resistant bacterial strains, enormous efforts are being conducted to identify suitable alternative agents against pathogenic microorganisms.
Patrizia D’Aquila +6 more
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Advancing aquaculture probiotic discovery via an innovative protocol for isolation of indigenous, heat and salt tolerant, quorum quenching probiotic candidates. [PDF]
Front MicrobiolIntroduction The intensification of aquaculture to meet the growing demand for aquatic animal protein by a global population approaching 10 billion by 2050 has raised concerns about the increased risk of disease outbreaks in farmed species.
Rwezawula P +4 more
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Quorum Sensing and Quorum Quenching with a Focus on Cariogenic and Periodontopathic Oral Biofilms [PDF]
Microorganisms, 2022 Numerous in vitro studies highlight the role of quorum sensing in the pathogenicity and virulence of biofilms. This narrative review discusses general principles in quorum sensing, including Gram-positive and Gram-negative models and the influence of ...
Patricia P. Wright +1 more
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A Novel and Efficient Platform for Discovering Noncanonical Quorum-Quenching Proteins [PDF]
Microbiology Spectrum, 2023 Quorum sensing (QS) is a well-known chemical signaling system responsible for intercellular communication that is widespread in bacteria. Acyl-homoserine lactone (AHL) is the most-studied QS signal.
Jinxing Liao +7 more
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Critical Assessment of the Prospects of Quorum-Quenching Therapy for Staphylococcus aureus Infection. [PDF]
Int J Mol Sci, 2023 Staphylococcus aureus is an important pathogen that causes a high number of infections and is one of the leading causes of death in hospitalized patients. Widespread antibiotic resistance such as in methicillin-resistant S.
Otto M.
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Innovative microbial disease biocontrol strategies mediated by quorum quenching and their multifaceted applications: A review. [PDF]
Front Plant Sci, 2022 With the increasing resistance exhibited by undesirable bacteria to traditional antibiotics, the need to discover alternative (or, at least, supplementary) treatments to combat chemically resistant bacteria is becoming urgent.
Zhu X +8 more
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Quorum quenching effect of cyclodextrins on the pyocyanin and pyoverdine production of Pseudomonas aeruginosa. [PDF]
Appl Microbiol BiotechnolVarious virulence determinants in Pseudomonas aeruginosa are regulated by the quorum sensing (QS) network producing and releasing signalling molecules.
Fekete-Kertész I +5 more
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Engineering quorum quenching acylases with improved kinetic and biochemical properties. [PDF]
Protein SciMany Gram‐negative bacteria use N‐acyl‐L‐homoserine lactone (AHL) signals to coordinate phenotypes such as biofilm formation and virulence factor production.
Sompiyachoke K, Elias MH.
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