Results 61 to 70 of about 10,756 (214)

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source

Advancing Antibiotic-Resistant Microbe Combat: Nanocarrier-Based Systems in Combination Therapy Targeting Quorum Sensing

Pharmaceutics
The increase in antibiotic-resistant bacteria presents a significant risk to worldwide public health, emphasizing the necessity of novel approaches to address infections.
Sanchaita Rajkhowa, Safrina Zeenat Hussain, Manisha Agarwal, Alaiha Zaheen, Sami A. Al-Hussain, Magdi E. A. Zaki   +5 more
doaj   +1 more source

Drugs for the Quorum Sensing Inhibition of Oral Biofilm: New Frontiers and Insights in the Treatment of Periodontitis

Pharmaceutics, 2022
Chemical molecules are used by microorganisms to communicate with each other. Quorum sensing is the mechanism through which microorganisms regulate their population density and activity with chemical signaling.
Alessandro Polizzi, Martina Donzella, Giada Nicolosi, Simona Santonocito, Paolo Pesce, Gaetano Isola   +5 more
doaj   +1 more source

Biotechnological applications of functional metagenomics in the food and pharmaceutical industries [PDF]

, 2015
peer-reviewedMicroorganisms are found throughout nature, thriving in a vast range of environmental conditions. The majority of them are unculturable or difficult to culture by traditional methods.
Alvarez-Ordonez, Avelino, Cotter, Paul D., Coughlan, Laura M., Hill, Colin   +3 more
core   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima, Luiz Otávio Guimarães‐Ervilha, Isabela Pereira da Silva Bento, Renê Chagas da Silva, Mariana Machado‐Neves   +4 more
wiley   +1 more source

Quorum-quenching microbial infections: mechanisms and implications [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2007
The discovery of antibiotics early in the past century marked the beginning of active control and prevention of infectious microbial diseases. However, extensive use of antibiotics has also unavoidably resulted in the emergence of ‘superbugs’ that resist conventional antibiotics.
Y-h, Dong, L-y, Wang, L-H, Zhang
openaire   +2 more sources

Reidite Formation From Zircon Subjected to 20, 40, and 60 GPa Shock Experiments

Journal of Raman Spectroscopy, EarlyView.
Structure disordering as a result of shock pressure: In zircon shocked from 20 to 60 GPa, the shock‐induced structural disorder increases with increasing shock pressure (gray area). Shock disorder of zircon is an integral part of its transformation to reidite: Reidite occurs after amorphous material.
Dmitry A. Zamyatin, Elizaveta Kovaleva
wiley   +1 more source

Structural and Biochemical Characterization of AaL, a Quorum Quenching Lactonase with Unusual Kinetic Properties

Scientific Reports, 2018
Quorum quenching lactonases are enzymes that are capable of disrupting bacterial signaling based on acyl homoserine lactones (AHL) via their enzymatic degradation.
Celine Bergonzi, Michael Schwab, Tanushree Naik, David Daudé, Eric Chabrière, Mikael Elias   +5 more
doaj   +1 more source

Quorum Quenching of Nitrobacter winogradskyi Suggests that Quorum Sensing Regulates Fluxes of Nitrogen Oxide(s) during Nitrification

mBio, 2016
Quorum sensing (QS) is a widespread process in bacteria used to coordinate gene expression with cell density, diffusion dynamics, and spatial distribution through the production of diffusible chemical signals.
Brett L. Mellbye, Andrew T. Giguere, Peter J. Bottomley, Luis A. Sayavedra-Soto   +3 more
doaj   +1 more source

Non-antibiotic quorum sensing inhibitors acting against N-acyl homoserine lactone synthase as druggable target [PDF]

, 2014
YesN-acylhomoserine lactone (AHL)-based quorum sensing (QS) is important for the regulation of proteobacterial virulence determinants. Thus, the inhibition of AHL synthases offers non-antibiotics-based therapeutic potentials against QS-mediated bacterial
A Dürig, B Prithiviraj, C Fuqua, C Niu, C-L Koh, C-Y Chang, CA Ortori, CM Wu, D Martinelli, E Déziel, G Brackman, G Jones, J Chung, JC Taganna, JE González, KH McClean, LCM Antunes, LM Guzman, M Cámara, M Hentzer, M Manefield, M Manefield, M Ndagijimana, MBK Bandara, ME Shirtliff, MK Winson, MR Parsek, MR Parsek, MW Calfee, P Williams, R Daniels, R García-Contreras, S Swift, S Uroz, T Das, T Krishnan, T Maeda, T Rudrappa, TA Gould, TA Gould, TT Hoang, VE Wagner, WT Watson, Y-H Lin, YH Dong, YH Dong, YM Chong   +46 more
core   +2 more sources