Cloning, Expression And Characterization Of Ahlinactivating aiiA Gene Homologue In Escherichia coli [PDF]
Cell-to-cell communication pathway of single-celled microbes is usually coordinated by quorum sensing (QS) system mediated by signal molecules. This cell density-dependent system plays a vital role in functional coordination of most pathogenic ...
Subashini, Muniandy
core
High throughput genomic sequencing of bioaerosols in broiler chicken production facilities [PDF]
Chronic inhalation exposure to agricultural dust promotes the development of chronic respiratory diseases among poultry workers. Poultry dust is composed of dander, chicken feed, litter bedding and microbes.
Bair, Thomas +6 more
core +2 more sources
Sustainable Photoinduced Frontal Polymerization of Acrylic Resins Reinforced by Biofillers
Top left: Chemical structures of the monomers and initiators used. Top right: Effect of monomer ratios on frontal velocity. Bottom left: Schematic overview of the PIFP process as the reaction front moves within the mold. Bottom right: Application of PIFP for wood repair.
Huseyin Mirac Dizman +2 more
wiley +1 more source
High‐Throughput Screening Reveals That CeeNU Acts as a New NLRP3 Inflammasome Inhibitor
We conducted a high‐throughput screen of 2747 FDA‐approved drugs to identify inhibitors of pyroptosis. We found that CeeNU significantly repressed NLRP3‐dependent IL‐1β release and GSDMD pore‐forming complex. We identified that the arginine 335 amino acid of the NACHT domain of NLRP3 is the critical point for human NLRP3 and CeeNU interaction and ...
Sen‐Lin Ji +11 more
wiley +1 more source
Quorum Quenching in Culturable Phyllosphere Bacteria from Tobacco [PDF]
Many Gram-negative plant pathogenic bacteria employ a N-acylhomoserine lactone (AHL)-based quorum sensing (QS) system to regulate their virulence traits. A sustainable biocontrol strategy has been developed using quorum quenching (QQ) bacteria to interfere with QS and protect plants from pathogens. Here, the prevalence and the diversity of QQ strains
Ma, Anzhou +3 more
openaire +2 more sources
Purification and Structural Analysis of QS-inhibiting Compounds from Staphylococcus delphini
The knowledge that many pathogens rely on cell-to-cell communication mechanisms known as quorum sensing, opens a new disease control strategy: quorum quenching.
Ya-Yun Chu +2 more
doaj +1 more source
Interference of Quorum Sensing by Delftia sp. VM4 Depends on the Activity of a Novel N-Acylhomoserine Lactone-Acylase. [PDF]
Turf soil bacterial isolate Delftia sp. VM4 can degrade exogenous N-acyl homoserine lactone (AHL), hence it effectively attenuates the virulence of bacterial soft rot pathogen Pectobacterium carotovorum subsp.
Vimal B Maisuria, Anuradha S Nerurkar
doaj +1 more source
Coumarin reduces virulence and biofilm formation in Pseudomonas aeruginosa by affecting quorum sensing, type III secretion and C-di-GMP levels [PDF]
As one of the major pathogens in wound infections, Pseudomonas aeruginosa produces several virulence factors and forms biofilms; these processes are under the regulation of various quorum sensing (QS) systems.
Coenye, Tom +8 more
core +3 more sources
Abstract Acyl‐CoA thioesterases hydrolyse thioester bonds to release free fatty acyl chains and coenzyme A (CoA), thereby regulating lipid metabolism, signaling, and membrane homeostasis. Here, we present the structural and functional characterization of the Paal‐like thioesterase SAV0944 (SaPaaI) from Staphylococcus aureus.
Yogesh Khandokar +5 more
wiley +1 more source
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li +9 more
wiley +1 more source

