Results 81 to 90 of about 10,681 (223)

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel, Manuel J. Verganista, Nuno R. Candeias   +2 more
wiley   +1 more source

Quorum Quenching in Culturable Phyllosphere Bacteria from Tobacco [PDF]

International Journal of Molecular Sciences, 2013
Many Gram-negative plant pathogenic bacteria employ a N-acylhomoserine lactone (AHL)-based quorum sensing (QS) system to regulate their virulence traits. A sustainable biocontrol strategy has been developed using quorum quenching (QQ) bacteria to interfere with QS and protect plants from pathogens. Here, the prevalence and the diversity of QQ strains
Ma, Anzhou, Lv, Di, Zhuang, Xuliang, Zhuang, Guoqiang   +3 more
openaire   +2 more sources

Introducing Pure Calcium Orthophosphate Gels and Aerogels

Advanced Functional Materials, Volume 36, Issue 23, 19 March 2026.
The synthesis of calcium phosphate‐based gels and aerogels is reported, which exhibit highly porous structures built up of networks of nanoparticles. In case of amorphous aerogels, this leads to yet unmatched specific BET surface areas, making these materials especially interesting for biomedical applications.
Oliver Jeske, Dominik Zanker, Nina Ehlert, Bing‐Qiang Lu, Denis Gebauer   +4 more
wiley   +1 more source

Purification and Structural Analysis of QS-inhibiting Compounds from Staphylococcus delphini

Bio-Protocol, 2014
The knowledge that many pathogens rely on cell-to-cell communication mechanisms known as quorum sensing, opens a new disease control strategy: quorum quenching.
Ya-Yun Chu, Mulugeta Nega, Friedrich Götz   +2 more
doaj   +1 more source

Interference of Quorum Sensing by Delftia sp. VM4 Depends on the Activity of a Novel N-Acylhomoserine Lactone-Acylase. [PDF]

PLoS ONE, 2015
Turf soil bacterial isolate Delftia sp. VM4 can degrade exogenous N-acyl homoserine lactone (AHL), hence it effectively attenuates the virulence of bacterial soft rot pathogen Pectobacterium carotovorum subsp.
Vimal B Maisuria, Anuradha S Nerurkar
doaj   +1 more source

Proton Motive Force-Dependent Hoechst 33342 Transport by the ABC Transporter LmrA of Lactococcus lactis [PDF]

, 2005
The fluorescent compound Hoechst 33342 is a substrate for many multidrug resistance (MDR) transporters and is widely used to characterize their transport activity.
Abbreviations ABC, Chen M., Doerrler W. T., Ecker G. F., Gajic O., Haugland R. P., Higuchi R., Ketchum C. J., Kuipers O. P., Lalande M. E., Lanzetta P. A., Lewinson O., Linnett P. E., Lubelski J., Lubelski J., Margolles A., Mazurkiewicz P., Orelle C., Paternostre M. T., Poelarends G. J., Putman M., Sakamoto K., Sambrook J., Shapiro A. B., Shapiro A. B., Shapiro A. B., Shapiro A. B., Sharma S., Steinfels E., Urbatsch I. L., van Veen H. W., van Veen H. W., van Veen H. W., Venter H., Viitanen P., Yu J. L.   +35 more
core   +2 more sources

A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids

Advanced Healthcare Materials, Volume 15, Issue 11, 20 March 2026.
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova, Fatemeh Ahmadi, Jennifer Cruickshank, Zheyuan Miao, Mariia Moshkova, Iuliia Pilipenko, David W. Cescon, Eugenia Kumacheva   +7 more
wiley   +1 more source

Artificial Symbiosis for Bulk Production of Bacterial Cellulose Composites

Advanced Materials, Volume 38, Issue 13, 3 March 2026.
Co‐cultivation of the cellulose‐producing bacterium with the microalga enables bulk formation of bacterial cellulose under static incubation, with photosynthetically active oxygen‐generating sites throughout the medium. This symbiotic platform supports 3D cellulosic constructs with geometries dictated by the vessel shape.
Kui Yu, Sing Teng Chua, Ran Zhao, Alyssa Smith, Michael Kühl, Alison G. Smith, Tom Ellis, Silvia Vignolini   +7 more
wiley   +1 more source

Discovery of new diketopiperazines inhibiting Burkholderia cenocepacia quorum sensing in vitro and in vivo [PDF]

, 2016
Burkholderia cenocepacia, an opportunistic respiratory pathogen particularly relevant for cystic fibrosis patients, is difficult to eradicate due to its high level of resistance to most clinically relevant antimicrobials.
Azzalin, Alberto, Brackman, Gilles, Buroni, Silvia, Chiarelli, Laurent R, Coenye, Tom, Forneris, Federico, Israyilova, Aygun, Makarov, Vadim, Riabova, Olga, Riccardi, Giovanna, Savina, Sventlana, Scoffone, Viola C   +11 more
core   +2 more sources

Evaluation of biological and enzymatic quorum quencher coating additives to reduce biocorrosion of steel.

PLoS ONE, 2019
Microbial colonization can be detrimental to the integrity of metal surfaces and lead to microbiologically influenced corrosion (MIC). Biocorrosion is a serious problem for aquatic and marine industries in the world.
Siqian Huang, Celine Bergonzi, Michael Schwab, Mikael Elias, Randall E Hicks   +4 more
doaj   +1 more source