Repurposing MK-8245 as a Quorum Sensing Inhibitor to Suppress Virulence and Potentiate Antibiotic Activity in <i>Pseudomonas aeruginosa</i>. [PDF]
Bernabè G +7 more
europepmc +1 more source
Ricinus Communis: Nutritional Importance, Health Benefits, and Industrial Applications
The current paper summarizes the nutritional composition, phytochemistry, health benefits, safety studies, and applications of castor beans and their oil. Moreover, the diverse bioactive compounds, including saponins, emodins, terpenoids, anthraquinones, flavonoids, steroids, and alkaloids, exhibit therapeutic properties such as antioxidant, anticancer,
Hassan Raza +13 more
wiley +1 more source
AHL quorum sensing regulates T6SS and volatiles production in rice root-colonizing Enterobacter asburiae AG129. [PDF]
Kumar C +6 more
europepmc +1 more source
A newly established 3D correlative cryogenic fluorescence microscopy, focused ion beam scanning electron microscopy, and soft x‐ray tomography workflow allowed for enough contrast and resolution to quantify the intracellular uptake of zirconyl‐containing inorganic–organic hybrid nanoparticles as a novel chemotherapeutic drug delivery system into ...
Pavitra Sokke Rudraiah +7 more
wiley +1 more source
Synergistic inhibition of agr quorum sensing in methicillin-resistant <i>Staphylococcus aureus</i>: a novel approach with natural compound encapsulation. [PDF]
Naderi K +3 more
europepmc +1 more source
Frontiers in the Management of Orthopaedic Periprosthetic Joint Infection
ABSTRACT Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA), one of the most frequently performed surgical procedures worldwide. Management of acute PJI commonly involves debridement, antibiotics, and implant retention (DAIR), though failure rates remain high due to antibiotic‐tolerant biofilms. Chronic
Michael F. Shannon +9 more
wiley +1 more source
Structure-function studies of Vibrio cholerae quorum-sensing receptor CqsR signal recognition. [PDF]
Guarnaccia AM +6 more
europepmc +1 more source
Explore the key challenges and limitations in nanomedicine for biofilm treatment, from drug loading efficiency to antimicrobial resistance. ABSTRACT Antimicrobial resistance continues to rise globally, with biofilm‐associated infections intensifying the clinical burden through persistent tolerance to antibiotics and evasion of immune responses ...
Husni Farah +8 more
wiley +1 more source
Quorum Sensing via Autoinducer-2 Promotes Colonisation and Host Adaptation in B. bifidum PRL2010. [PDF]
Turroni F +11 more
europepmc +1 more source

