Growing emergence of drug-resistant Pseudomonas aeruginosa and attenuation of its virulence using quorum sensing inhibitors: A critical review. [PDF]
Bhardwaj S, Bhatia S, Singh S, Franco F.
europepmc +1 more source
Graphical overview of bioinspired regenerative platforms designed to remodel the diseased lung microenvironment. These systems integrate gene addition, siRNA‐mediated transcript silencing, CRISPR‐based modulation, and base editing approaches to promote alveolar repair, AT2‐to‐AT1 regeneration, resolution of inflammation, and restoration of vascular ...
Kajal Kamra, Sonal Gaur, Jaswinder Singh
wiley +1 more source
Protocol for in silico characterization of natural-based molecules as quorum-sensing inhibitors. [PDF]
Fernandes S +4 more
europepmc +1 more source
Synthesis of thiophenones as quorum sensing inhibitors
Bacteria communicate using small signaling molecules as part of a system of communication called quorum sensing (QS) to control gene expression for synchronized bacterial behaviors. A task performed by bacteria that is often controlled by this means is biofilm production, making bacteria more resistant to external factors. Naturally occurring furanones
openaire +1 more source
Garlic bioactive compounds, including organosulfur compounds (allicin, DADS, DATS, and SAC), phenolic compounds, and quercetin, regulate the Nrf2/HO‐1, NF‐κB, PI3K/Akt, and AMPK/eNOS signaling pathways. These actions enhance antioxidant defenses, suppress inflammation, improve metabolic and cardiovascular function, and contribute to reduced blood ...
Gudisa Bereda
wiley +1 more source
Novel 1,3,4-oxadiazole-nicotinamide hybrids as non-classical AHL mimics quorum sensing inhibitors of Pseudomonas aeruginosa: design, synthesis and biological evaluation. [PDF]
Hamoud MMS +7 more
europepmc +1 more source
Natural and Enantiopure Alkylglycerols as Antibiofilms Against Clinical Bacterial Isolates and Quorum Sensing Inhibitors of Chromobacterium violaceum ATCC 12472. [PDF]
Chaverra Daza KE +3 more
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Environmental Drivers of Nontuberculous Mycobacteria in Tropical Freshwater Systems
In tropical freshwater ecosystems, nontuberculous mycobacterial diversity and distribution is mainly driven by habitat and sample type, and local environmental factors such as sediment texture and depth. These findings highlight the importance of microhabitat conditions over broad biogeographic patterns in shaping mycobacterial communities.
Marine Combe +8 more
wiley +1 more source
Design, Synthesis, and Biological Evaluation of the Quorum-Sensing Inhibitors of Pseudomonas aeruginosa PAO1. [PDF]
Yan X +6 more
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