The selective nature through which coumarin compounds produced by different species of plants target PQS signalling in Pseudomonas aeruginosa and select for distinct phenotypic responses in key pathogenic organisms adds to the growing evidence of their utility as natural virulence suppressors. ABSTRACT Cell‐to‐cell communication in microbial systems is
Dylan Boon +8 more
wiley +1 more source
Exploring propolis-derived compounds as quorum sensing inhibitors for Candida albicans: a molecular docking and dynamics simulations study. [PDF]
Chraa F +9 more
europepmc +1 more source
Evaluation of Novel Quorum Sensing Inhibitors Targeting Auto-Inducer 2 (AI-2) for the Control of Avian Pathogenic Escherichia coli Infections in Chickens. [PDF]
Helmy YA +8 more
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Summary Beneficial, facultative endophytes help plants thrive in challenging environments by altering their host's metabolism, but how these cellular scale metabolic changes propagate to the systems biology scale is unknown. In this work, we employed a high‐resolution chemical imaging approach to map metabolic changes at the Populus trichocarpa root ...
Jayde Aufrecht +9 more
wiley +1 more source
Bitter taste receptors (T2Rs) play an important role in physiological and cellular responses. Bitter tasting chemicals and microbial metabolites can bind to T2R14, which enables interactions between T2R14 and specific intracellular domains of the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel.
Tejas Gupte +8 more
wiley +1 more source
2-Difluoromethylpyridine as a bioisosteric replacement of pyridine-N-oxide: the case of quorum sensing inhibitors. [PDF]
Tung TT, Nguyen Quoc T.
europepmc +1 more source
Novel 1,3,4-oxadiazole-nicotinamide hybrids as non-classical AHL mimics quorum sensing inhibitors of Pseudomonas aeruginosa: design, synthesis and biological evaluation. [PDF]
Hamoud MMS +7 more
europepmc +1 more source
Growing emergence of drug-resistant Pseudomonas aeruginosa and attenuation of its virulence using quorum sensing inhibitors: A critical review. [PDF]
Bhardwaj S, Bhatia S, Singh S, Franco F.
europepmc +1 more source
Synthesis of thiophenones as quorum sensing inhibitors
Bacteria communicate using small signaling molecules as part of a system of communication called quorum sensing (QS) to control gene expression for synchronized bacterial behaviors. A task performed by bacteria that is often controlled by this means is biofilm production, making bacteria more resistant to external factors. Naturally occurring furanones
openaire +1 more source
Electrospun tubular scaffolds from novel PBCE‐based copolyesters and blends were designed as candidates for small‐diameter vascular grafts. They combine defect‐free architecture, blood‐compatible surfaces, and mechanical properties comparable to native vessels.
Edoardo Bondi +7 more
wiley +1 more source

