Results 161 to 170 of about 1,595,844 (248)

Exploring propolis-derived compounds as quorum sensing inhibitors for Candida albicans: a molecular docking and dynamics simulations study. [PDF]

Sci Rep
Chraa F, EL Meskini D, Kandoussi I, Bouyahya A, Ming LC, Chew J, Moshawih S, Jaoudi RE, Ouadghiri M, Aanniz T.   +9 more
europepmc   +1 more source

Quorum Sensing Inhibitors: Curbing Pathogenic Infections through Inhibition of Bacterial Communication. [PDF]

Iran J Pharm Res, 2021
Singh S, Bhatia S.
europepmc   +1 more source

Biosynthetic Pathways and Regulation of Antibacterial Compounds From Endophytic Fungi: From Chemistry to Genomics and Biotechnology

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Endophytic fungi encode abundant cryptic biosynthetic gene clusters that remain largely silent under conventional cultivation. This review highlights how genome mining, multi‐omics, and cluster activation strategies bridge the BGC‐to‐metabolite gap, enabling the discovery of structurally diverse antibacterial natural products with activity against ...
Farkhod Eshboev, Abubakar Siddiq Salihu, Lobar Khayrullaeva, Doniyor Khamdamov, Alex X. Gao, Kamila Mardieva, Wan Mohd Nuzul Hakimi Wan Salleh, Shakhnoz Azimova, Karl W. K. Tsim   +8 more
wiley   +1 more source

Design, Synthesis, Biological Evaluation, and In Silico Study of N-(Pyrazin-2-yl)Alkyl/Aryl Amide Derivatives as Quorum Sensing Inhibitors Against Pseudomonas aeruginosa. [PDF]

Chem Biodivers
Yadav A, Mahindru I, Srivastava N, Kumar R, Jain M, Kumar L, Yadav AK.   +6 more
europepmc   +1 more source

2-Difluoromethylpyridine as a bioisosteric replacement of pyridine-N-oxide: the case of quorum sensing inhibitors. [PDF]

RSC Med Chem, 2021
Tung TT, Nguyen Quoc T.
europepmc   +1 more source

Piezo1‐mediated unfolded protein response in goblet cells regulates intestinal mucus barrier homeostasis through the Ca2+–IRE1α–XBP1 pathway

Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.
This study demonstrates that activation of Piezo1 channels in goblet cells by intestinal mechanical stimulation modulates ER calcium homeostasis via calcium ion (Ca2+) flux, which in turn regulates Mucin2 production and synthesis through the IRE1α‐XBP1. Intraperitoneal administration of Yoda1 alleviates mucus barrier impairment in DSS/WAS‐treated mice.
Jiandi Wu, Shaotong Wang, Zhe Wang, Jianhua Fang, Xueyan Li, Qingqing Zhang, Yan Dai, Wenjing Tian, Yize Ma, Gangping Li, Lei Zhang, Yudong Jiang, Xiaohua Hou, Jun Song   +13 more
wiley   +1 more source

Garlic-Derived Quorum Sensing Inhibitors: A Novel Strategy Against Fungal Resistance. [PDF]

Drug Des Devel Ther
Li N, Zhang J, Yu F, Ye F, Tan W, Hao L, Li S, Deng J, Hu X.   +8 more
europepmc   +1 more source

Evaluation of Novel Quorum Sensing Inhibitors Targeting Auto-Inducer 2 (AI-2) for the Control of Avian Pathogenic Escherichia coli Infections in Chickens. [PDF]

Microbiol Spectr, 2022
Helmy YA, Kathayat D, Deblais L, Srivastava V, Closs G, Tokarski RJ, Ayinde O, Fuchs JR, Rajashekara G.   +8 more
europepmc   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

Journal of Applied Toxicology, Volume 46, Issue 11, Page 3868-3881, November 2026.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima, Luiz Otávio Guimarães‐Ervilha, Isabela Pereira da Silva Bento, Renê Chagas da Silva, Mariana Machado‐Neves   +4 more
wiley   +1 more source

Integrative In vitro and In Silico analysis of marine Actinobacterium, <i>Streptomyces rubrogriseus</i>-derived metabolites as quorum sensing inhibitors against <i>Chromobacterium violaceum</i>. [PDF]

Toxicol Res (Camb)
Balakrishnan A, Nevin KG, Gangadharan A, Limnamol VP.   +3 more
europepmc   +1 more source